Gene description for ATAD2 |
Gene name |
ATPase family, AAA domain containing 2 |
Gene symbol |
ATAD2 |
Other names/aliases |
ANCCA CT137 PRO2000 |
Species |
Homo sapiens |
Database cross references - ATAD2 |
ExoCarta |
ExoCarta_29028 |
Entrez Gene |
29028 |
HGNC |
30123 |
MIM |
611941 |
UniProt |
Q6PL18
|
ATAD2 identified in exosomes derived from the following tissue/cell type |
Hepatocellular carcinoma cells
|
26054723
|
Urine
|
19056867
|
Gene ontology annotations for ATAD2 |
|
Experiment description of studies that identified ATAD2 in exosomes |
1 |
Experiment ID |
235 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix|HSC70|GAPDH
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✔
HSP90B1
|
EV Negative markers |
✔
qNano
|
EV Particle analysis
|
|
Identified molecule |
mRNA
|
Identification method |
RNA Sequencing
|
PubMed ID |
26054723
|
Organism |
Homo sapiens |
Experiment description |
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs |
Authors |
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N |
Journal name |
Carcinogenesis
|
Publication year |
2015 |
Sample |
Hepatocellular carcinoma cells |
Sample name |
HKCI-8 |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.13-1.19 g/mL
|
Molecules identified in the study |
Protein RNA |
Methods used in the study |
Western blotting Mass spectrometry RT-PCR RNA Sequencing |
|
|
2 |
Experiment ID |
63 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
AQP2
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
19056867
|
Organism |
Homo sapiens |
Experiment description |
Large-scale proteomics and phosphoproteomics of urinary exosomes. |
Authors |
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA |
Journal name |
JASN
|
Publication year |
2009 |
Sample |
Urine |
Sample name |
Urine - Normal |
Isolation/purification methods |
Differential centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [LTQ] Western blotting |
|
|
Protein-protein interactions for ATAD2 |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which ATAD2 is involved |
No pathways found
|
|
|