Gene description for Eif6
Gene name
eukaryotic translation initiation factor 6
Gene symbol
Eif6
Other names/aliases
1110004P11 AA408895 CAB Itgb4bp eIF-6 imc-415 p27(BBP) p27BBP
Species
Mus musculus
Database cross references - Eif6
ExoCarta
ExoCarta_16418
Vesiclepedia
VP_16418
Entrez Gene
16418
UniProt
O55135
Eif6 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Eif6
Experiment description of studies that identified Eif6 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Eif6
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Psme1
19186
Co-fractionation
Mus musculus
2
Elf5
Affinity Capture-MS
Mus musculus
3
Atxn1
Affinity Capture-MS
Mus musculus
4
Rpl19
19921
Co-fractionation
Mus musculus
5
Eed
Affinity Capture-MS
Mus musculus
6
Rpl12
269261
Co-fractionation
Mus musculus
7
Rpl6
19988
Co-fractionation
Mus musculus
8
Atg16l1
Affinity Capture-MS
Mus musculus
9
Rpl7
19989
Co-fractionation
Mus musculus
10
Rplp2
67186
Co-fractionation
Mus musculus
11
Nanog
Affinity Capture-MS
Mus musculus
12
Fancd2
Affinity Capture-MS
Mus musculus
13
Rpl30
19946
Co-fractionation
Mus musculus
14
Rpl13
270106
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Eif6 is involved
No pathways found