Gene description for Glg1
Gene name golgi apparatus protein 1
Gene symbol Glg1
Other names/aliases AI593353
AW537898
CFR
CFR-1
ESL-1
MG-160
MG160
Selel
Species Mus musculus
 Database cross references - Glg1
ExoCarta ExoCarta_20340
Vesiclepedia VP_20340
Entrez Gene 20340
UniProt Q61543  
 Glg1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Glg1
Molecular Function
    fibroblast growth factor binding GO:0017134 IBA
    fibroblast growth factor binding GO:0017134 ISO
Biological Process
    transforming growth factor beta receptor signaling pathway GO:0007179 IMP
    negative regulation of protein processing GO:0010955 IGI
    negative regulation of protein processing GO:0010955 IMP
    protein processing GO:0016485 IGI
    protein processing GO:0016485 IMP
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IMP
    regulation of chondrocyte differentiation GO:0032330 IMP
    bone morphogenesis GO:0060349 IMP
Subcellular Localization
    Golgi membrane GO:0000139 IBA
    Golgi membrane GO:0000139 IDA
    Golgi apparatus GO:0005794 IDA
    Golgi apparatus GO:0005794 ISO
    Golgi medial cisterna GO:0005797 ISO
    microtubule organizing center GO:0005815 IEA
    plasma membrane GO:0005886 IEA
    extracellular matrix GO:0031012 IDA
 Experiment description of studies that identified Glg1 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Glg1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Nms  
Co-fractionation Mus musculus
2 Pars2  
Co-fractionation Mus musculus
3 Uggt1 320011
Co-fractionation Mus musculus
4 Tmem38b  
Co-fractionation Mus musculus
5 Atg5  
Affinity Capture-RNA Mus musculus
6 Atg16l1  
Affinity Capture-MS Mus musculus
7 Abhd10  
Co-fractionation Mus musculus
8 Ngly1  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Glg1 is involved
PathwayEvidenceSource
Cell surface interactions at the vascular wall IEA Reactome
Hemostasis IEA Reactome





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