Gene description for Ubd
Gene name ubiquitin D
Gene symbol Ubd
Other names/aliases FAT10
Species Mus musculus
 Database cross references - Ubd
ExoCarta ExoCarta_24108
Vesiclepedia VP_24108
Entrez Gene 24108
UniProt P63072  
 Ubd identified in sEVs derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Ubd
Molecular Function
    protein binding GO:0005515 IPI
    proteasome binding GO:0070628 IBA
    proteasome binding GO:0070628 ISO
    proteasome binding GO:0070628 ISS
Biological Process
    ubiquitin-dependent protein catabolic process GO:0006511 IBA
    ubiquitin-dependent protein catabolic process GO:0006511 IMP
    ubiquitin-dependent protein catabolic process GO:0006511 ISO
    protein ubiquitination GO:0016567 IBA
    protein ubiquitination GO:0016567 IMP
    protein ubiquitination GO:0016567 ISO
    protein modification by small protein conjugation GO:0032446 IC
    response to type II interferon GO:0034341 IBA
    response to type II interferon GO:0034341 IEP
    response to tumor necrosis factor GO:0034612 IBA
    response to tumor necrosis factor GO:0034612 IEP
    myeloid dendritic cell differentiation GO:0043011 ISO
    myeloid dendritic cell differentiation GO:0043011 ISS
    positive regulation of apoptotic process GO:0043065 IBA
    positive regulation of apoptotic process GO:0043065 IEP
    positive regulation of apoptotic process GO:0043065 IMP
    positive regulation of apoptotic process GO:0043065 ISO
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 IBA
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 IMP
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 ISO
    aggresome assembly GO:0070842 ISO
    aggresome assembly GO:0070842 ISS
    regulation of mitotic cell cycle phase transition GO:1901990 ISO
    regulation of mitotic cell cycle phase transition GO:1901990 ISS
Subcellular Localization
    fibrillar center GO:0001650 IEA
    fibrillar center GO:0001650 ISO
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 IDA
    aggresome GO:0016235 IEA
    aggresome GO:0016235 ISO
 Experiment description of studies that identified Ubd in sEVs
1
Experiment ID 33
MISEV standards
EM|IEM
Biophysical techniques
Alix|TSG101
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors "Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J"
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Ubd
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TGFBR1 7046
Affinity Capture-Luminescence Homo sapiens
View the network image/svg+xml
 Pathways in which Ubd is involved
PathwayEvidenceSource
Metabolism of proteins IEA Reactome
Neddylation IEA Reactome
Post-translational protein modification IEA Reactome





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