Gene description for PAMR1 |
Gene name |
peptidase domain containing associated with muscle regeneration 1 |
Gene symbol |
PAMR1 |
Other names/aliases |
DKFZP586H2123 FP938 RAMP |
Species |
Homo sapiens |
Database cross references - PAMR1 |
ExoCarta |
ExoCarta_25891 |
Vesiclepedia |
VP_25891 |
Entrez Gene |
25891 |
HGNC |
24554 |
UniProt |
Q6UXH9
|
PAMR1 identified in sEVs derived from the following tissue/cell type |
Mesenchymal stem cells
|
36408942
|
Squamous carcinoma cells
|
20124223
|
Gene ontology annotations for PAMR1 |
|
Experiment description of studies that identified PAMR1 in sEVs |
1 |
Experiment ID |
488 |
MISEV standards |
✔
EM
|
Biophysical techniques |
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
|
Enriched markers |
✔
CANX
|
Negative markers |
✔
NTA
|
Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
36408942
|
Organism |
Homo sapiens |
Experiment description |
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells |
Authors |
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." |
Journal name |
Proteomics
|
Publication year |
2023 |
Sample |
Mesenchymal stem cells |
Sample name |
UCMSC |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectometry |
|
|
2 |
Experiment ID |
191 |
MISEV standards |
✘
|
Biophysical techniques |
✔
Alix|CD81|CD9
|
Enriched markers |
✘
|
Negative markers |
✘
|
Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
20124223
|
Organism |
Homo sapiens |
Experiment description |
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. |
Authors |
"Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK." |
Journal name |
Mol Cell Proteomics
|
Publication year |
2010 |
Sample |
Squamous carcinoma cells |
Sample name |
Squamous carcinoma cell (A431) |
Isolation/purification methods |
Differential centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
Protein-protein interactions for PAMR1 |
|
Pathways in which PAMR1 is involved |
No pathways found
|
|
|