Gene description for C3orf38
Gene name chromosome 3 open reading frame 38
Gene symbol C3orf38
Other names/aliases -
Species Homo sapiens
 Database cross references - C3orf38
ExoCarta ExoCarta_285237
Vesiclepedia VP_285237
Entrez Gene 285237
HGNC 28384
UniProt Q5JPI3  
 C3orf38 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for C3orf38
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    apoptotic process GO:0006915 IEA
    positive regulation of apoptotic process GO:0043065 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
 Experiment description of studies that identified C3orf38 in sEVs
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for C3orf38
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STUB1 10273
Affinity Capture-MS Homo sapiens
2 ALAS1  
Affinity Capture-MS Homo sapiens
3 HSPA6 3310
Affinity Capture-MS Homo sapiens
4 HSPA8 3312
Affinity Capture-MS Homo sapiens
5 TCEAL5  
Affinity Capture-MS Homo sapiens
6 SLC19A3  
Two-hybrid Homo sapiens
7 BAG1 573
Affinity Capture-MS Homo sapiens
8 HSPA2 3306
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 TMEM87A 25963
Affinity Capture-MS Homo sapiens
10 DNAJB5  
Affinity Capture-MS Homo sapiens
11 DNAJB4 11080
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 BAG4  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
13 BAG2 9532
Affinity Capture-MS Homo sapiens
14 HSPA1A 3303
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which C3orf38 is involved
No pathways found





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