Gene description for Tagln3
Gene name transgelin 3
Gene symbol Tagln3
Other names/aliases 2700038H05Rik
2900005O10Rik
AI426007
Np25
Species Mus musculus
 Database cross references - Tagln3
ExoCarta ExoCarta_56370
Vesiclepedia VP_56370
Entrez Gene 56370
UniProt Q9R1Q8  
 Tagln3 identified in sEVs derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Tagln3
Molecular Function
    molecular_function GO:0003674 ND
    actin filament binding GO:0051015 IBA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    actin filament organization GO:0007015 IBA
Subcellular Localization
    nucleus GO:0005634 IDA
    actin cytoskeleton GO:0015629 IBA
    myelin sheath GO:0043209 HDA
    synapse GO:0045202 EXP
    synapse GO:0045202 IDA
    synapse GO:0045202 IMP
 Experiment description of studies that identified Tagln3 in sEVs
1
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tagln3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
2 Mycbp2 105689
Affinity Capture-MS Mus musculus
3 Rtn1  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Tagln3 is involved
No pathways found





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