Gene description for ICAM5
Gene name intercellular adhesion molecule 5, telencephalin
Gene symbol ICAM5
Other names/aliases TLCN
TLN
Species Homo sapiens
 Database cross references - ICAM5
ExoCarta ExoCarta_7087
Vesiclepedia VP_7087
Entrez Gene 7087
HGNC 5348
MIM 601852
UniProt Q9UMF0  
 ICAM5 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ICAM5
Molecular Function
    integrin binding GO:0005178 IBA
    protein binding GO:0005515 IPI
Biological Process
    phagocytosis GO:0006909 IEA
    cell adhesion GO:0007155 IBA
    regulation of synapse assembly GO:0051963 IEA
    cell-cell adhesion GO:0098609 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    postsynapse GO:0098794 IEA
    glutamatergic synapse GO:0098978 IEA
 Experiment description of studies that identified ICAM5 in sEVs
1
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ICAM5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LY86  
Affinity Capture-MS Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 CD14 929
Affinity Capture-MS Homo sapiens
4 Sgol2  
Affinity Capture-MS Mus musculus
5 PSEN1 5663
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
6 HYAL1 3373
Affinity Capture-MS Homo sapiens
7 TCTN1  
Affinity Capture-MS Homo sapiens
8 LGALS1 3956
Affinity Capture-MS Homo sapiens
9 STAT5A 6776
Affinity Capture-MS Homo sapiens
10 Sart3  
Affinity Capture-MS Mus musculus
11 GGH 8836
Affinity Capture-MS Homo sapiens
12 PNPLA5  
Affinity Capture-MS Homo sapiens
13 LGALS3 3958
Affinity Capture-MS Homo sapiens
14 PDGFRA 5156
Affinity Capture-MS Homo sapiens
15 Rmdn3  
Affinity Capture-MS Mus musculus
16 PRG2  
Affinity Capture-MS Homo sapiens
17 CBR1 873
Affinity Capture-MS Homo sapiens
18 Shoc2  
Affinity Capture-MS Mus musculus
19 FBXO6 26270
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 AQP3  
Affinity Capture-MS Homo sapiens
21 SLURP1  
Affinity Capture-MS Homo sapiens
22 NAF1  
Affinity Capture-MS Homo sapiens
23 PSEN2 5664
Reconstituted Complex Homo sapiens
24 BAG6 7917
Affinity Capture-MS Homo sapiens
25 APEX1 328
Affinity Capture-RNA Homo sapiens
26 HSPA12A 259217
Affinity Capture-MS Homo sapiens
27 TUBA4A 7277
Affinity Capture-MS Homo sapiens
28 RNASEH2A 10535
Affinity Capture-MS Homo sapiens
29 ARMC6 93436
Affinity Capture-MS Homo sapiens
30 TM2D3  
Affinity Capture-MS Homo sapiens
31 TMEM132A 54972
Affinity Capture-MS Homo sapiens
32 YAP1 10413
Affinity Capture-MS Homo sapiens
33 FBXO2 26232
Affinity Capture-MS Homo sapiens
34 SORT1 6272
Affinity Capture-MS Homo sapiens
35 CARKD 55739
Affinity Capture-MS Homo sapiens
36 Kif13b  
Affinity Capture-MS Mus musculus
37 Zbtb48  
Affinity Capture-MS Mus musculus
38 PTPN4  
Affinity Capture-MS Homo sapiens
39 GML  
Affinity Capture-MS Homo sapiens
40 OXCT2  
Affinity Capture-MS Homo sapiens
41 DNASE1L1 1774
Affinity Capture-MS Homo sapiens
42 ILK 3611
Affinity Capture-MS Homo sapiens
43 LGALS8 3964
Affinity Capture-MS Homo sapiens
44 IL5RA  
Affinity Capture-MS Homo sapiens
45 PTCH1  
Affinity Capture-MS Homo sapiens
46 PARD6B 84612
Affinity Capture-MS Homo sapiens
47 KIF18A  
Affinity Capture-MS Homo sapiens
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