Experiment description of studies that identified Cep55 in sEVs

1 Experiment ID 907 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample Colon cancer cells Sample name C26 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 214 MISEV standards ✔ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23658846     Organism Mus musculus Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Authors "Hassani K, Olivier M." Journal name PLoS Negl Trop Dis Publication year 2013 Sample Macrophages Sample name Leishmania-infected-Macrophage (J774A.1) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 215 MISEV standards ✔ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23658846     Organism Mus musculus Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Authors "Hassani K, Olivier M." Journal name PLoS Negl Trop Dis Publication year 2013 Sample Macrophages Sample name LPS-treated-Macrophage (J774A.1) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 216 MISEV standards ✔ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23658846     Organism Mus musculus Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Authors "Hassani K, Olivier M." Journal name PLoS Negl Trop Dis Publication year 2013 Sample Macrophages Sample name Normal-Macrophage (J774A.1) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

5 Experiment ID 908 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample T-cell lymphoma cells Sample name EL4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for Cep55

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CHMP2A 27243 Affinity Capture-MS Homo sapiens 2 ATP6V1B2 526 Affinity Capture-MS Homo sapiens 3 ZNF624 57547 Affinity Capture-MS Homo sapiens 4 HNRNPC 3183 Affinity Capture-MS Homo sapiens 5 KNSTRN   Affinity Capture-MS Homo sapiens 6 CEP131 22994 Affinity Capture-MS Homo sapiens 7 PDLIM1 9124 Affinity Capture-MS Homo sapiens 8 VPS28 51160 Affinity Capture-MS Homo sapiens 9 VPS37C 55048 Affinity Capture-MS Homo sapiens 10 PDCD6IP 10015 Affinity Capture-MS Homo sapiens 11 RACGAP1 29127 Affinity Capture-MS Homo sapiens 12 CEP55 55165 Affinity Capture-MS Homo sapiens 13 SPAG5 10615 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 CHMP2B 25978 Affinity Capture-MS Homo sapiens 15 CD2AP 23607 Affinity Capture-MS Homo sapiens 16 TSG101 7251 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 IKBIP 121457 Affinity Capture-MS Homo sapiens 18 PTP4A1 7803 Affinity Capture-MS Homo sapiens 19 FTH1 2495 Affinity Capture-MS Homo sapiens 20 CDK1 983 Affinity Capture-MS Homo sapiens 21 Tmem173   Proximity Label-MS Mus musculus 22 CLASP1 23332 Affinity Capture-MS Homo sapiens 23 MAP7D1 55700 Affinity Capture-MS Homo sapiens 24 UMAD1   Affinity Capture-MS Homo sapiens 25 GCC2 9648 Affinity Capture-MS Homo sapiens 26 PCBP1 5093 Affinity Capture-MS Homo sapiens 27 CHMP4B 128866 Affinity Capture-MS Homo sapiens 28 CEP170 9859 Affinity Capture-MS Homo sapiens 29 IST1 9798 Affinity Capture-MS Homo sapiens 30 SET 6418 Affinity Capture-MS Homo sapiens 31 INTS7   Affinity Capture-MS Homo sapiens 32 HNRNPA1L2 144983 Affinity Capture-MS Homo sapiens 33 FBXO28   Affinity Capture-MS Homo sapiens 34 GNB2L1 10399 Affinity Capture-MS Homo sapiens 35 PCM1 5108 Affinity Capture-MS Homo sapiens 36 CTSZ 1522 Affinity Capture-MS Homo sapiens 37 CEP72   Affinity Capture-MS Homo sapiens 38 MAGED2 10916 Affinity Capture-MS Homo sapiens 39 MVB12A 93343 Affinity Capture-MS Homo sapiens 40 AP5M1 55745 Affinity Capture-MS Homo sapiens 41 CCDC61   Affinity Capture-MS Homo sapiens 42 GPRC5A 9052 Affinity Capture-MS Homo sapiens 43 PAXIP1   Affinity Capture-MS Homo sapiens View the network

Pathways in which Cep55 is involved

No pathways found