Gene description for Naa15
Gene name N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Gene symbol Naa15
Other names/aliases 5730450D16Rik
6330400I15
ASTBDN
Narg1
Tbdn-1
mNAT1
Species Mus musculus
 Database cross references - Naa15
ExoCarta ExoCarta_74838
Vesiclepedia VP_74838
Entrez Gene 74838
 Naa15 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Naa15
Molecular Function
    protein binding GO:0005515 IPI
    N-acetyltransferase activity GO:0008080 IDA
    acetyltransferase activator activity GO:0010698 IBA
    acetyltransferase activity GO:0016407 ISO
    ribosome binding GO:0043022 ISO
    ribosome binding GO:0043022 ISO
Biological Process
    angiogenesis GO:0001525 IEA
    N-terminal protein amino acid acetylation GO:0006474 ISO
    cell differentiation GO:0030154 IEA
    negative regulation of apoptotic process GO:0043066 ISO
    positive regulation of DNA-templated transcription GO:0045893 ISO
    protein stabilization GO:0050821 ISO
Subcellular Localization
    nucleus GO:0005634 IEA
    nucleus GO:0005634 ISO
    transcription regulator complex GO:0005667 ISO
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
    nuclear body GO:0016604 ISO
    NatA complex GO:0031415 IBA
    NatA complex GO:0031415 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified Naa15 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Naa15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TBX3 6926
Affinity Capture-MS Homo sapiens
2 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
3 NUDT3 11165
Affinity Capture-MS Homo sapiens
4 Naa10  
Reconstituted Complex Mus musculus
5 CWC15  
Affinity Capture-MS Homo sapiens
6 NAA15 80155
Affinity Capture-MS Homo sapiens
7 LRRFIP2 9209
Affinity Capture-MS Homo sapiens
8 Eed  
Affinity Capture-MS Mus musculus
9 PPIL2  
Affinity Capture-MS Homo sapiens
10 NAA50 80218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 PHACTR4 65979
Affinity Capture-MS Homo sapiens
12 Ewsr1 14030
Two-hybrid Mus musculus
13 RAB11FIP2  
Affinity Capture-MS Homo sapiens
14 HYPK 25764
Affinity Capture-MS Homo sapiens
15 NAA10 8260
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 GTF3C2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Naa15 is involved
No pathways found





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