Gene description for Prss23
Gene name protease, serine 23
Gene symbol Prss23
Other names/aliases 2310046G15Rik
4930479H08Rik
AI790574
Spuve
Species Mus musculus
 Database cross references - Prss23
ExoCarta ExoCarta_76453
Vesiclepedia VP_76453
Entrez Gene 76453
UniProt Q9D6X6  
 Prss23 identified in sEVs derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Prss23
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
Biological Process
    proteolysis GO:0006508 IEA
Subcellular Localization
    extracellular space GO:0005615 HDA
    nucleus GO:0005634 IEA
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Prss23 in sEVs
1
Experiment ID 263
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Prss23
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Odf2l  
Co-fractionation Mus musculus
2 Grk6 26385
Co-fractionation Mus musculus
3 Tcf12 21406
Co-fractionation Mus musculus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here