Gene description for TANGO6
Gene name transport and golgi organization 6 homolog (Drosophila)
Gene symbol TANGO6
Other names/aliases TMCO7
Species Homo sapiens
 Database cross references - TANGO6
ExoCarta ExoCarta_79613
Vesiclepedia VP_79613
Entrez Gene 79613
HGNC 25749
UniProt Q9C0B7  
 TANGO6 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for TANGO6
Biological Process
    protein secretion GO:0009306 IBA
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified TANGO6 in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TANGO6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DNAJC7 7266
Affinity Capture-MS Homo sapiens
2 POLR2B 5431
Affinity Capture-MS Homo sapiens
3 POLR2J  
Affinity Capture-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 SPATA5L1 79029
Affinity Capture-MS Homo sapiens
6 UBE2S  
Co-fractionation Homo sapiens
7 CIB2  
Affinity Capture-MS Homo sapiens
8 NSUN5P1  
Affinity Capture-MS Homo sapiens
9 PPM1M  
Affinity Capture-MS Homo sapiens
10 FBXW5  
Affinity Capture-MS Homo sapiens
11 FAM167A  
Affinity Capture-MS Homo sapiens
12 HSPA8 3312
Affinity Capture-MS Homo sapiens
13 UBE3A 7337
Affinity Capture-MS Homo sapiens
14 BAG2 9532
Affinity Capture-MS Homo sapiens
15 RUVBL2 10856
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 DNAJA2 10294
Affinity Capture-MS Homo sapiens
17 TSSK6 83983
Affinity Capture-MS Homo sapiens
18 MACF1 23499
Two-hybrid Homo sapiens
19 ZNHIT2 741
Proximity Label-MS Homo sapiens
20 WDR92 116143
Affinity Capture-MS Homo sapiens
21 FAM96A  
Affinity Capture-MS Homo sapiens
22 SULT1C4  
Affinity Capture-MS Homo sapiens
23 HDHD1  
Affinity Capture-MS Homo sapiens
24 OFCC1  
Affinity Capture-MS Homo sapiens
25 POLR2K  
Affinity Capture-MS Homo sapiens
26 CAPZA2 830
Affinity Capture-MS Homo sapiens
27 EGFR 1956
Negative Genetic Homo sapiens
28 MTNR1B  
Two-hybrid Homo sapiens
29 TFPT  
Affinity Capture-MS Homo sapiens
30 LOXL4 84171
Affinity Capture-MS Homo sapiens
31 B4GALT2  
Affinity Capture-MS Homo sapiens
32 ALDH3B1 221
Affinity Capture-MS Homo sapiens
33 GALNT12 79695
Affinity Capture-MS Homo sapiens
34 URI1  
Affinity Capture-MS Homo sapiens
35 C6orf141  
Affinity Capture-MS Homo sapiens
36 GPN2  
Affinity Capture-MS Homo sapiens
37 RUVBL1 8607
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 C12orf74  
Affinity Capture-MS Homo sapiens
39 INF2 64423
Affinity Capture-MS Homo sapiens
40 SOHLH1  
Affinity Capture-MS Homo sapiens
41 AMZ1  
Affinity Capture-MS Homo sapiens
42 VWA2 340706
Affinity Capture-MS Homo sapiens
43 P4HA2 8974
Affinity Capture-MS Homo sapiens
44 MMP28  
Affinity Capture-MS Homo sapiens
45 CDK20  
Affinity Capture-MS Homo sapiens
46 RPAP3 79657
Affinity Capture-MS Homo sapiens
47 RANGRF  
Affinity Capture-MS Homo sapiens
48 SNX21  
Affinity Capture-MS Homo sapiens
49 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
50 SF3B3 23450
Affinity Capture-MS Homo sapiens
51 KLF6  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
52 MAGEA4 4103
Affinity Capture-MS Homo sapiens
53 PTPN18 26469
Affinity Capture-MS Homo sapiens
54 TRMU  
Affinity Capture-MS Homo sapiens
55 SERBP1 26135
Affinity Capture-MS Homo sapiens
56 UBXN6 80700
Affinity Capture-MS Homo sapiens
57 UPP1 7378
Affinity Capture-MS Homo sapiens
58 ATG7 10533
Affinity Capture-MS Homo sapiens
59 KLHL14 57565
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TANGO6 is involved
No pathways found





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