Gene description for GRTP1
Gene name growth hormone regulated TBC protein 1
Gene symbol GRTP1
Other names/aliases TBC1D6
Species Homo sapiens
 Database cross references - GRTP1
ExoCarta ExoCarta_79774
Vesiclepedia VP_79774
Entrez Gene 79774
HGNC 20310
UniProt Q5TC63  
 GRTP1 identified in sEVs derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for GRTP1
Molecular Function
    GTPase activator activity GO:0005096 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified GRTP1 in sEVs
1
Experiment ID 211
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GRTP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TBRG1  
Affinity Capture-MS Homo sapiens
2 NES 10763
Affinity Capture-MS Homo sapiens
3 FAM63A 55793
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 GJB7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 UBB 7314
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 PCDHGC3 5098
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 MAGEA3  
Affinity Capture-MS Homo sapiens
8 ATP2A1 487
Affinity Capture-MS Homo sapiens
9 FBXL19  
Affinity Capture-MS Homo sapiens
10 KIF14 9928
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GRTP1 is involved
No pathways found





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