Gene description for BICC1
Gene name BicC family RNA binding protein 1
Gene symbol BICC1
Other names/aliases BICC
CYSRD
Species Homo sapiens
 Database cross references - BICC1
ExoCarta ExoCarta_80114
Vesiclepedia VP_80114
Entrez Gene 80114
HGNC 19351
MIM 614295
UniProt Q9H694  
 BICC1 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for BICC1
Molecular Function
    RNA binding GO:0003723 HDA
Biological Process
    kidney development GO:0001822 IEA
    determination of left/right symmetry GO:0007368 IEA
    heart development GO:0007507 IEA
    negative regulation of canonical Wnt signaling pathway GO:0090090 IDA
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified BICC1 in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for BICC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TFG 10342
Affinity Capture-MS Homo sapiens
2 NUP35 129401
Proximity Label-MS Homo sapiens
3 ANKS3  
Affinity Capture-MS Homo sapiens
4 Cep152  
Affinity Capture-MS Mus musculus
5 CAPZA2 830
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which BICC1 is involved
No pathways found





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