Gene description for CNTNAP4
Gene name contactin associated protein-like 4
Gene symbol CNTNAP4
Other names/aliases CASPR4
Species Homo sapiens
 Database cross references - CNTNAP4
ExoCarta ExoCarta_85445
Vesiclepedia VP_85445
Entrez Gene 85445
HGNC 18747
MIM 610518
UniProt Q9C0A0  
 CNTNAP4 identified in sEVs derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for CNTNAP4
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cell adhesion GO:0007155 IEA
    regulation of synaptic transmission, dopaminergic GO:0032225 ISS
    regulation of synaptic transmission, GABAergic GO:0032228 ISS
    regulation of grooming behavior GO:2000821 ISS
Subcellular Localization
    presynaptic membrane GO:0042734 ISS
    cell projection GO:0042995 IEA
 Experiment description of studies that identified CNTNAP4 in sEVs
1
Experiment ID 274
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
 Protein-protein interactions for CNTNAP4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CASK 8573
Reconstituted Complex Homo sapiens
2 CHMP4C 92421
Affinity Capture-MS Homo sapiens
3 PRC1 9055
Affinity Capture-MS Homo sapiens
4 ANLN 54443
Affinity Capture-MS Homo sapiens
5 FBXO21  
Two-hybrid Homo sapiens
6 AURKB 9212
Affinity Capture-MS Homo sapiens
7 APBA1  
Reconstituted Complex Homo sapiens
8 MAST3  
Two-hybrid Homo sapiens
9 KIF20A 10112
Affinity Capture-MS Homo sapiens
10 NELFE 7936
Affinity Capture-MS Homo sapiens
11 BCL7C  
Affinity Capture-MS Homo sapiens
12 KIF23 9493
Affinity Capture-MS Homo sapiens
13 KIF14 9928
Affinity Capture-MS Homo sapiens
14 RANBP10 57610
Two-hybrid Homo sapiens
15 FOLR1 2348
Affinity Capture-MS Homo sapiens
16 MACF1 23499
Two-hybrid Homo sapiens
17 CIT 11113
Affinity Capture-MS Homo sapiens
18 ECT2 1894
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CNTNAP4 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here