Gene description for Slc6a20a
Gene name solute carrier family 6 (neurotransmitter transporter), member 20A
Gene symbol Slc6a20a
Other names/aliases A730081N20Rik
AU022428
Xt3s1
Xtrp3s1
Species Mus musculus
 Database cross references - Slc6a20a
ExoCarta ExoCarta_102680
Entrez Gene 102680
UniProt Q8VDB9  
 Slc6a20a identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Slc6a20a
Molecular Function
    amino acid transmembrane transporter activity GO:0015171 ISO
    neurotransmitter:sodium symporter activity GO:0005328 IEA
    symporter activity GO:0015293 IEA
Biological Process
    transport GO:0006810 IEA
    neurotransmitter transport GO:0006836 IEA
    glycine transport GO:0015816 ISO
    proline transport GO:0015824 ISO
    amino acid transport GO:0006865 ISO
    amino acid transmembrane transport GO:0003333 ISO
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    integral component of plasma membrane GO:0005887 IEA
    plasma membrane GO:0005886 IEA
    membrane GO:0016020 IEA
    apical plasma membrane GO:0016324 IDA
 Experiment description of studies that identified Slc6a20a in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Slc6a20a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc6a20a is involved
PathwayEvidenceSource
Amino acid transport across the plasma membrane IEA Reactome
Na+/Cl- dependent neurotransmitter transporters IEA Reactome





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