Gene description for Tmed4
Gene name transmembrane emp24 protein transport domain containing 4
Gene symbol Tmed4
Other names/aliases 1110014L17Rik
AI326346
Species Mus musculus
 Database cross references - Tmed4
ExoCarta ExoCarta_103694
Entrez Gene 103694
UniProt Q8R1V4  
 Tmed4 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Tmed4
Molecular Function
    signal transducer activity GO:0004871 ISO
Biological Process
    protein transport GO:0015031 IEA
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISO
    signal transduction GO:0007165 ISO
    transport GO:0006810 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    endoplasmic reticulum GO:0005783 IEA
    extracellular exosome GO:0070062 ISO
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Tmed4 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tmed4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmed4 is involved
No pathways found





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