Gene description for Mrps6
Gene name mitochondrial ribosomal protein S6
Gene symbol Mrps6
Other names/aliases AW046321
Species Mus musculus
 Database cross references - Mrps6
ExoCarta ExoCarta_121022
Entrez Gene 121022
UniProt P58064  
 Mrps6 identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Mrps6
Molecular Function
    small ribosomal subunit rRNA binding GO:0070181 IBA
    rRNA binding GO:0019843 IEA
    structural constituent of ribosome GO:0003735 IBA
Biological Process
    translation GO:0006412 IEA
Subcellular Localization
    ribosome GO:0005840 IEA
    ribonucleoprotein complex GO:0030529 IEA
    mitochondrial small ribosomal subunit GO:0005763 IBA
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified Mrps6 in exosomes
1
Experiment ID 264
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Mrps6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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