Gene description for Cdc25c
Gene name cell division cycle 25C
Gene symbol Cdc25c
Other names/aliases Cdc25
Species Mus musculus
 Database cross references - Cdc25c
ExoCarta ExoCarta_12532
Entrez Gene 12532
UniProt P48967  
 Cdc25c identified in exosomes derived from the following tissue/cell type
Mast cells 11145662    
 Gene ontology annotations for Cdc25c
Molecular Function
    protein tyrosine phosphatase activity GO:0004725 IEA
    WW domain binding GO:0050699 ISO
    hydrolase activity GO:0016787 IEA
    protein kinase binding GO:0019901 ISO
    phosphoprotein phosphatase activity GO:0004721 IEA
    protein binding GO:0005515 IPI
Biological Process
    protein dephosphorylation GO:0006470 IEA
    mitotic nuclear division GO:0007067 IEA
    G2/M transition of mitotic cell cycle GO:0000086 ISO
    cell division GO:0051301 IEA
    mitotic M phase GO:0000087 IEA
    cell cycle GO:0007049 IEA
Subcellular Localization
    perinuclear region of cytoplasm GO:0048471 ISO
    intracellular GO:0005622 IEA
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Cdc25c in exosomes
1
Experiment ID 5
ISEV standards
✔
EM|IEM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD86|CD80
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 11145662    
Organism Mus musculus
Experiment description Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes.
Authors Skokos D, Le Panse S, Villa I, Rousselle JC, Peronet R, David B, Namane A, Mecheri S
Journal name JIMMU
Publication year 2001
Sample Mast cells
Sample name P815
MC9
Bone marrow-derived mast cells
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
ELISA
 Protein-protein interactions for Cdc25c
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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