Gene description for Cmas
Gene name cytidine monophospho-N-acetylneuraminic acid synthetase
Gene symbol Cmas
Other names/aliases AW208911
CMPNeu5Ac
D6Bwg0250e
Species Mus musculus
 Database cross references - Cmas
ExoCarta ExoCarta_12764
Entrez Gene 12764
UniProt Q99KK2  
 Cmas identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cmas
Molecular Function
    transferase activity GO:0016740 IEA
    nucleotidyltransferase activity GO:0016779 IEA
    N-acylneuraminate cytidylyltransferase activity GO:0008781 ISA
Biological Process
    CMP-N-acetylneuraminate biosynthetic process GO:0006055 ISA
Subcellular Localization
    nucleus GO:0005634 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Cmas in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cmas
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cmas is involved
PathwayEvidenceSource
Sialic acid metabolism IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here