Gene description for Sypl
Gene name synaptophysin-like protein
Gene symbol Sypl
Other names/aliases AI314763
AI604763
D12Ertd446e
PanI
Pphn
Sypl1
Species Mus musculus
 Database cross references - Sypl
ExoCarta ExoCarta_19027
Entrez Gene 19027
UniProt O09117  
 Sypl identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Sypl
Molecular Function
    transporter activity GO:0005215 IEA
Biological Process
    transport GO:0006810 IEA
Subcellular Localization
    secretory granule GO:0030141 IDA
    cytoplasmic vesicle GO:0031410 IEA
    integral component of synaptic vesicle membrane GO:0030285 IBA
    membrane GO:0016020 IDA
    synaptic vesicle GO:0008021 IEA
    integral component of membrane GO:0016021 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Sypl in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Sypl
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sypl is involved
No pathways found





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