Gene description for Cdh13
Gene name cadherin 13
Gene symbol Cdh13
Other names/aliases Cdht
T-cadherin
Tcad
Species Rattus norvegicus
 Database cross references - Cdh13
ExoCarta ExoCarta_192248
Entrez Gene 192248
 Cdh13 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Cdh13
Molecular Function
    molecular_function GO:0003674 ND
    low-density lipoprotein particle binding GO:0030169 ISO
    cadherin binding GO:0045296 ISO
    protein homodimerization activity GO:0042803 ISO
    calcium ion binding GO:0005509 IEA
    adiponectin binding GO:0055100 ISO
    lipoprotein particle binding GO:0071813 ISO
Biological Process
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO
    response to organic substance GO:0010033 IEP
    cell adhesion GO:0007155 NAS
    regulation of cell growth GO:0001558 IMP
    positive regulation of positive chemotaxis GO:0050927 ISO
    positive regulation of endothelial cell proliferation GO:0001938 ISO
    endothelial cell migration GO:0043542 ISO
    positive regulation of cell-matrix adhesion GO:0001954 ISO
    Rac protein signal transduction GO:0016601 ISO
    low-density lipoprotein particle mediated signaling GO:0055096 ISO
    negative regulation of cell adhesion GO:0007162 ISO
    positive regulation of smooth muscle cell proliferation GO:0048661 ISO
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 ISO
    single organismal cell-cell adhesion GO:0016337 TAS
    negative regulation of cell proliferation GO:0008285 ISO
    sprouting angiogenesis GO:0002040 ISO
    localization within membrane GO:0051668 ISO
    regulation of epidermal growth factor receptor signaling pathway GO:0042058 ISO
    keratinocyte proliferation GO:0043616 ISO
    regulation of endocytosis GO:0030100 ISO
    lamellipodium assembly GO:0030032 ISO
    Rho protein signal transduction GO:0007266 ISO
    mitotic cell cycle GO:0000278 IEP
    positive regulation of calcium-mediated signaling GO:0050850 ISO
    calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339 ISO
    positive regulation of cell migration GO:0030335 ISO
Subcellular Localization
    focal adhesion GO:0005925 ISO
    external side of plasma membrane GO:0009897 ISO
    cytoplasm GO:0005737 ISO
    neuron projection GO:0043005 ISO
    extracellular exosome GO:0070062 ISO
    caveola GO:0005901 ISO
    perinuclear region of cytoplasm GO:0048471 IDA
    plasma membrane GO:0005886 ISO
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Cdh13 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Cdh13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cdh13 is involved
No pathways found





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