Gene description for EGFR
Gene name epidermal growth factor receptor
Gene symbol EGFR
Other names/aliases ERBB
ERBB1
HER1
NISBD2
PIG61
mENA
Species Homo sapiens
 Database cross references - EGFR
ExoCarta ExoCarta_1956
Vesiclepedia VP_1956
Entrez Gene 1956
HGNC 3236
MIM 131550
UniProt P00533  
 EGFR identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 30918259    
Breast cancer cells 30918259    
Colon cancer cells 34887515    
Colon cancer cells 34887515    
Colon cancer cells 34887515    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Keratinocytes 19530224    
Keratinocytes 19530224    
Lung cancer cells 31792209    
Lung cancer cells 33686255    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Nasopharyngeal carcinoma cells 21059916    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 21763319    
Pancreatic cancer cells 21763319    
Pancreatic cancer cells 21763319    
Pancreatic cancer cells 21763319    
Pancreatic cancer cells 21763319    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Serum 19109410    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for EGFR
Molecular Function
    virus receptor activity GO:0001618 IEA
    chromatin binding GO:0003682 IDA
    double-stranded DNA binding GO:0003690 NAS
    MAP kinase kinase kinase activity GO:0004709 NAS
    protein tyrosine kinase activity GO:0004713 IDA
    protein tyrosine kinase activity GO:0004713 IMP
    protein tyrosine kinase activity GO:0004713 TAS
    transmembrane receptor protein tyrosine kinase activity GO:0004714 IBA
    transmembrane receptor protein tyrosine kinase activity GO:0004714 TAS
    transmembrane signaling receptor activity GO:0004888 IDA
    GPI-linked ephrin receptor activity GO:0005004 IEA
    transmembrane-ephrin receptor activity GO:0005005 IEA
    epidermal growth factor receptor activity GO:0005006 IDA
    epidermal growth factor receptor activity GO:0005006 IDA
    epidermal growth factor receptor activity GO:0005006 IMP
    epidermal growth factor receptor activity GO:0005006 NAS
    fibroblast growth factor receptor activity GO:0005007 IEA
    hepatocyte growth factor receptor activity GO:0005008 IEA
    insulin receptor activity GO:0005009 IEA
    insulin-like growth factor receptor activity GO:0005010 IEA
    macrophage colony-stimulating factor receptor activity GO:0005011 IEA
    platelet-derived growth factor alpha-receptor activity GO:0005018 IEA
    platelet-derived growth factor beta-receptor activity GO:0005019 IEA
    stem cell factor receptor activity GO:0005020 IEA
    vascular endothelial growth factor receptor activity GO:0005021 IEA
    integrin binding GO:0005178 IEA
    protein binding GO:0005515 IPI
    calmodulin binding GO:0005516 IEA
    ATP binding GO:0005524 IEA
    boss receptor activity GO:0008288 IEA
    enzyme binding GO:0019899 IPI
    kinase binding GO:0019900 IPI
    protein kinase binding GO:0019901 IEA
    protein phosphatase binding GO:0019903 IPI
    protein tyrosine kinase activator activity GO:0030296 IDA
    ubiquitin protein ligase binding GO:0031625 IPI
    histone H3Y41 kinase activity GO:0035401 IEA
    placental growth factor receptor activity GO:0036332 IEA
    protein tyrosine kinase collagen receptor activity GO:0038062 IEA
    identical protein binding GO:0042802 IPI
    cadherin binding GO:0045296 HDA
    epidermal growth factor binding GO:0048408 IBA
    actin filament binding GO:0051015 IDA
    ATPase binding GO:0051117 ISS
    brain-derived neurotrophic factor receptor activity GO:0060175 IEA
    histone H2AXY142 kinase activity GO:0140801 IEA
Biological Process
    MAPK cascade GO:0000165 IEA
    ossification GO:0001503 NAS
    embryonic placenta development GO:0001892 IEA
    positive regulation of protein phosphorylation GO:0001934 IDA
    hair follicle development GO:0001942 IEA
    chromatin remodeling GO:0006338 IEA
    translation GO:0006412 IEA
    response to oxidative stress GO:0006979 IEA
    signal transduction GO:0007165 IDA
    signal transduction GO:0007165 TAS
    cell surface receptor signaling pathway GO:0007166 IDA
    cell surface receptor protein tyrosine kinase signaling pathway GO:0007169 IBA
    epidermal growth factor receptor signaling pathway GO:0007173 IDA
    epidermal growth factor receptor signaling pathway GO:0007173 IDA
    epidermal growth factor receptor signaling pathway GO:0007173 IMP
    epidermal growth factor receptor signaling pathway GO:0007173 TAS
    multicellular organism development GO:0007275 IBA
    salivary gland morphogenesis GO:0007435 IEA
    midgut development GO:0007494 IEA
    learning or memory GO:0007611 ISS
    circadian rhythm GO:0007623 IEA
    positive regulation of cell population proliferation GO:0008284 IDA
    positive regulation of cell population proliferation GO:0008284 IMP
    insulin receptor signaling pathway GO:0008286 IEA
    fibroblast growth factor receptor signaling pathway GO:0008543 IEA
    diterpenoid metabolic process GO:0016101 IEA
    peptidyl-tyrosine phosphorylation GO:0018108 IDA
    cerebral cortex cell migration GO:0021795 IEA
    neurogenesis GO:0022008 IBA
    positive regulation of cell growth GO:0030307 IDA
    lung development GO:0030324 IEA
    positive regulation of cell migration GO:0030335 IMP
    brain-derived neurotrophic factor receptor signaling pathway GO:0031547 IEA
    positive regulation of superoxide anion generation GO:0032930 IEA
    positive regulation of peptidyl-serine phosphorylation GO:0033138 IMP
    response to cobalamin GO:0033590 IEA
    response to hydroxyisoflavone GO:0033594 IEA
    platelet-derived growth factor receptor-alpha signaling pathway GO:0035790 IEA
    platelet-derived growth factor receptor-beta signaling pathway GO:0035791 IEA
    vascular endothelial growth factor receptor-1 signaling pathway GO:0036323 IEA
    collagen-activated tyrosine kinase receptor signaling pathway GO:0038063 IEA
    peptidyl-tyrosine autophosphorylation GO:0038083 TAS
    vascular endothelial growth factor signaling pathway GO:0038084 IEA
    Kit signaling pathway GO:0038109 IEA
    ERBB2-EGFR signaling pathway GO:0038134 IDA
    macrophage colony-stimulating factor signaling pathway GO:0038145 IEA
    negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 TAS
    negative regulation of protein catabolic process GO:0042177 IDA
    vasodilation GO:0042311 IEA
    positive regulation of phosphorylation GO:0042327 IDA
    ovulation cycle GO:0042698 IEA
    hydrogen peroxide metabolic process GO:0042743 IEA
    negative regulation of apoptotic process GO:0043066 IBA
    negative regulation of apoptotic process GO:0043066 IMP
    tongue development GO:0043586 IEA
    positive regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045737 IMP
    positive regulation of DNA repair GO:0045739 IDA
    positive regulation of DNA replication GO:0045740 IDA
    positive regulation of bone resorption GO:0045780 IEA
    positive regulation of vasoconstriction GO:0045907 IEA
    negative regulation of mitotic cell cycle GO:0045930 IEA
    positive regulation of transcription by RNA polymerase II GO:0045944 IDA
    symbiont entry into host cell GO:0046718 IEA
    insulin-like growth factor receptor signaling pathway GO:0048009 IEA
    hepatocyte growth factor receptor signaling pathway GO:0048012 IEA
    ephrin receptor signaling pathway GO:0048013 IEA
    astrocyte activation GO:0048143 IEA
    positive regulation of fibroblast proliferation GO:0048146 IEA
    digestive tract morphogenesis GO:0048546 IEA
    positive regulation of smooth muscle cell proliferation GO:0048661 IEA
    neuron projection morphogenesis GO:0048812 IEA
    epithelial cell proliferation GO:0050673 IEA
    positive regulation of epithelial cell proliferation GO:0050679 IBA
    positive regulation of epithelial cell proliferation GO:0050679 IDA
    regulation of peptidyl-tyrosine phosphorylation GO:0050730 IMP
    protein insertion into membrane GO:0051205 TAS
    response to calcium ion GO:0051592 IEA
    positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IMP
    positive regulation of synaptic transmission, glutamatergic GO:0051968 IEA
    positive regulation of glial cell proliferation GO:0060252 IEA
    morphogenesis of an epithelial fold GO:0060571 IEA
    eyelid development in camera-type eye GO:0061029 IEA
    response to UV-A GO:0070141 IDA
    positive regulation of mucus secretion GO:0070257 IEA
    positive regulation of ERK1 and ERK2 cascade GO:0070374 IDA
    positive regulation of ERK1 and ERK2 cascade GO:0070374 IMP
    cellular response to amino acid stimulus GO:0071230 IEA
    cellular response to mechanical stimulus GO:0071260 IEA
    cellular response to epidermal growth factor stimulus GO:0071364 ISS
    cellular response to estradiol stimulus GO:0071392 IDA
    cellular response to xenobiotic stimulus GO:0071466 IEA
    cellular response to dexamethasone stimulus GO:0071549 IEA
    positive regulation of canonical Wnt signaling pathway GO:0090263 IMP
    liver regeneration GO:0097421 IEA
    cell-cell adhesion GO:0098609 IMP
    positive regulation of protein kinase C activity GO:1900020 IDA
    positive regulation of G1/S transition of mitotic cell cycle GO:1900087 IMP
    positive regulation of prolactin secretion GO:1902722 IEA
    positive regulation of miRNA transcription GO:1902895 IMP
    positive regulation of protein localization to plasma membrane GO:1903078 IDA
    negative regulation of cardiocyte differentiation GO:1905208 IMP
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    extracellular space GO:0005615 NAS
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    endosome GO:0005768 IDA
    endosome GO:0005768 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    focal adhesion GO:0005925 HDA
    basal plasma membrane GO:0009925 IBA
    cell surface GO:0009986 IDA
    endosome membrane GO:0010008 IDA
    endosome membrane GO:0010008 TAS
    membrane GO:0016020 IDA
    basolateral plasma membrane GO:0016323 IDA
    apical plasma membrane GO:0016324 IEA
    cell junction GO:0030054 IDA
    clathrin-coated endocytic vesicle membrane GO:0030669 TAS
    early endosome membrane GO:0031901 IDA
    nuclear membrane GO:0031965 IEA
    ruffle membrane GO:0032587 IDA
    protein-containing complex GO:0032991 IDA
    receptor complex GO:0043235 IBA
    receptor complex GO:0043235 IDA
    membrane raft GO:0045121 IDA
    membrane raft GO:0045121 ISS
    perinuclear region of cytoplasm GO:0048471 IMP
    Shc-EGFR complex GO:0070435 ISS
    synaptic membrane GO:0097060 IEA
    multivesicular body, internal vesicle lumen GO:0097489 IDA
    intracellular vesicle GO:0097708 IDA
    glutamatergic synapse GO:0098978 IEA
 Experiment description of studies that identified EGFR in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 924
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|SDCBP|CD81|RAB35|LAMP2|FLOT1|TSG101|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 30918259    
Organism Homo sapiens
Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Authors "Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC."
Journal name Nat Commun
Publication year 2019
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 927
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|SDCBP|CD81|RAB35|LAMP2|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 30918259    
Organism Homo sapiens
Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Authors "Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC."
Journal name Nat Commun
Publication year 2019
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 1212
MISEV standards
✘ Biophysical techniques
✔
SDCBP
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colon cancer cells
Sample name LS174T
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
13
Experiment ID 1213
MISEV standards
✘ Biophysical techniques
✔
FLOT1|CD9|SDCBP
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colon cancer cells
Sample name DiFi-derived EGFR/CD81-positive sEVs - dim (FAVS)
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
14
Experiment ID 1214
MISEV standards
✘ Biophysical techniques
✔
EPCAM|FLOT1|CD9|SDCBP
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colon cancer cells
Sample name DiFi-derived EGFR/CD81-positive sEVs - bright (FAVS)
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
15
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
16
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
18
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
19
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 1219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Flow cytometry
PubMed ID 31792209    
Organism Homo sapiens
Experiment description Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles
Authors "Xie X, Nie H, Zhou Y, Lian S, Mei H, Lu Y, Dong H, Li F, Li T, Li B, Wang J, Lin M, Wang C, Shao J, Gao Y, Chen J, Xie F, Jia L."
Journal name Nat Commun
Publication year 2019
Sample Lung cancer cells
Sample name A549
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Flow cytometry
31
Experiment ID 1324
MISEV standards
Biophysical techniques
✔
GAPDH|CD63|LAMP1|FLOT1|TSG101|Alix
Enriched markers
✔
GAPDH|HSP90AA1
Negative markers
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33686255    
Organism Homo sapiens
Experiment description Extracellular vesicle drug occupancy enables real-time monitoring of targeted cancer therapy.
Authors "Pan S, Zhang Y, Natalia A, Lim CZJ, Ho NRY, Chowbay B, Loh TP, Tam JKC, Shao H."
Journal name Nat Nanotechnol
Publication year 2021
Sample Lung cancer cells
Sample name H3255
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
32
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
43
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 125
MISEV standards
✘ Biophysical techniques
✔
HSC70|GAPDH|FLOT2
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 21059916    
Organism Homo sapiens
Experiment description Human tumor virus utilizes exosomes for intercellular communication.
Authors "Meckes DG Jr, Shair KH, Marquitz AR, Kung CP, Edwards RH, Raab-Traub N."
Journal name PNAS
Publication year 2010
Sample Nasopharyngeal carcinoma cells
Sample name C666
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
45
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
48
Experiment ID 104
MISEV standards
✘ Biophysical techniques
✔
SDCBP
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 21763319    
Organism Homo sapiens
Experiment description Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors "Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I."
Journal name LS
Publication year 2011
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
49
Experiment ID 105
MISEV standards
✘ Biophysical techniques
✔
SDCBP
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 21763319    
Organism Homo sapiens
Experiment description Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors "Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I."
Journal name LS
Publication year 2011
Sample Pancreatic cancer cells
Sample name Paca44
Isolation/purification methods Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
50
Experiment ID 106
MISEV standards
✘ Biophysical techniques
✔
SDCBP
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 21763319    
Organism Homo sapiens
Experiment description Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors "Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I."
Journal name LS
Publication year 2011
Sample Pancreatic cancer cells
Sample name MiaPaca2
Isolation/purification methods Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
51
Experiment ID 107
MISEV standards
✘ Biophysical techniques
✔
SDCBP
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 21763319    
Organism Homo sapiens
Experiment description Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors "Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I."
Journal name LS
Publication year 2011
Sample Pancreatic cancer cells
Sample name A818-4
Isolation/purification methods Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
52
Experiment ID 103
MISEV standards
✘ Biophysical techniques
✔
Alix|SDCBP|CD63|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
Western blotting
PubMed ID 21763319    
Organism Homo sapiens
Experiment description Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.
Authors "Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnolzer M, Schwarte-Waldhoff I."
Journal name LS
Publication year 2011
Sample Pancreatic cancer cells
Sample name Panc1
Isolation/purification methods Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
53
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
54
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
56
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
57
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
58
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
59
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
60
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
61
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
62
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
63
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
64
Experiment ID 29
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19109410    
Organism Homo sapiens
Experiment description Proteomic and immunologic analyses of brain tumor exosomes.
Authors "Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD"
Journal name FASEB
Publication year 2008
Sample Serum
Sample name Serum - Brain tumor
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
65
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
66
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EGFR
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ACSL3 2181
Negative Genetic Homo sapiens
2 SEC16A 9919
Affinity Capture-MS Homo sapiens
3 GUK1 2987
Negative Genetic Homo sapiens
4 CAP1 10487
Negative Genetic Homo sapiens
5 SNRNP40 9410
Negative Genetic Homo sapiens
6 UBC 7316
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
7 VHL  
Negative Genetic Homo sapiens
8 DNAH8 1769
Affinity Capture-MS Homo sapiens
9 GCN1L1 10985
Affinity Capture-MS Homo sapiens
10 GRB7 2886
Reconstituted Complex Homo sapiens
11 MEAF6  
Negative Genetic Homo sapiens
12 DARS 1615
Affinity Capture-MS Homo sapiens
13 ISYNA1 51477
Negative Genetic Homo sapiens
14 SLC39A11  
Affinity Capture-MS Homo sapiens
15 CDH16  
Affinity Capture-MS Homo sapiens
16 GRIK4  
Affinity Capture-MS Homo sapiens
17 RPS9 6203
Negative Genetic Homo sapiens
18 PTPRR  
Two-hybrid Homo sapiens
19 ORC6  
Negative Genetic Homo sapiens
20 SFN 2810
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
21 ABHD17A 81926
Negative Genetic Homo sapiens
22 ELP6 54859
Negative Genetic Homo sapiens
23 WBP2 23558
Affinity Capture-Western Homo sapiens
24 STARD7 56910
Negative Genetic Homo sapiens
25 TFRC 7037
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
26 KIF14 9928
Affinity Capture-MS Homo sapiens
27 CAMLG 819
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
28 AP1S2 8905
Affinity Capture-MS Homo sapiens
29 PPM1B 5495
Two-hybrid Homo sapiens
30 AP3M1 26985
Affinity Capture-MS Homo sapiens
31 TCP1 6950
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
32 SRPRB 58477
Affinity Capture-MS Homo sapiens
33 TRAFD1  
Affinity Capture-MS Homo sapiens
34 CTBP1 1487
Affinity Capture-MS Homo sapiens
35 RRP9 9136
Negative Genetic Homo sapiens
36 BRE 9577
Affinity Capture-MS Homo sapiens
37 TUFM 7284
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
38 PPIH 10465
Negative Genetic Homo sapiens
39 HDAC7  
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
40 YAP1 10413
Affinity Capture-Western Homo sapiens
41 YRDC 79693
Negative Genetic Homo sapiens
42 MEGF6  
PCA Homo sapiens
43 RBM17 84991
Negative Genetic Homo sapiens
44 LOC101060321  
Negative Genetic Homo sapiens
45 ENO1 2023
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
46 RFC4 5984
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
47 SH2D2A  
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
48 CTDSPL 10217
Proximity Label-MS Homo sapiens
49 SEC61B 10952
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Negative Genetic Homo sapiens
50 ANLN 54443
Affinity Capture-MS Homo sapiens
51 SDHC 6391
Negative Genetic Homo sapiens
52 HSPA5 3309
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 RBM39 9584
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
54 KRT86  
Affinity Capture-MS Homo sapiens
55 PRKAR1A 5573
Affinity Capture-Western Homo sapiens
56 PRKCZ 5590
Two-hybrid Homo sapiens
PCA Homo sapiens
57 DIP2A 23181
Affinity Capture-MS Homo sapiens
58 WDR55  
Negative Genetic Homo sapiens
59 ATRIP  
Negative Genetic Homo sapiens
60 SPDYE2  
Negative Genetic Homo sapiens
61 AAAS 8086
Affinity Capture-MS Homo sapiens
62 EPRS 2058
Affinity Capture-MS Homo sapiens
63 PDGFRA 5156
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
64 NTHL1  
Affinity Capture-MS Homo sapiens
65 BLK 640
Protein-peptide Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Reconstituted Complex Homo sapiens
66 TUBA4A 7277
Affinity Capture-MS Homo sapiens
67 SAAL1 113174
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 STAT1 6772
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
69 CMSS1  
Affinity Capture-MS Homo sapiens
70 LTV1  
Negative Genetic Homo sapiens
71 GSTK1 373156
Affinity Capture-MS Homo sapiens
72 GRB14 2888
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
73 IL1RAPL2  
Affinity Capture-MS Homo sapiens
74 LGALS8 3964
Affinity Capture-MS Homo sapiens
75 AKT1 207
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
76 UPF2 26019
Negative Genetic Homo sapiens
77 RRAGC 64121
Negative Genetic Homo sapiens
78 STUB1 10273
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-Western Homo sapiens
79 HK2 3099
Affinity Capture-MS Homo sapiens
80 NOSIP 51070
Affinity Capture-MS Homo sapiens
81 YBX1 4904
Affinity Capture-MS Homo sapiens
82 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
83 IDH3B 3420
Affinity Capture-MS Homo sapiens
84 PTPRD 5789
Affinity Capture-MS Homo sapiens
85 RRS1 23212
Negative Genetic Homo sapiens
86 THOC3  
Negative Genetic Homo sapiens
87 WDR92 116143
Negative Genetic Homo sapiens
88 IRS2 8660
Affinity Capture-MS Homo sapiens
89 GRID1 2894
Affinity Capture-MS Homo sapiens
90 PPOX 5498
Negative Genetic Homo sapiens
91 DCTN2 10540
PCA Homo sapiens
Negative Genetic Homo sapiens
92 TBL3 10607
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
93 TRA2B 6434
Affinity Capture-MS Homo sapiens
94 OS9 10956
Affinity Capture-MS Homo sapiens
95 TUT1  
Negative Genetic Homo sapiens
96 SSBP1 6742
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
97 PMM2 5373
Affinity Capture-MS Homo sapiens
98 FAR1 84188
Affinity Capture-MS Homo sapiens
99 EIF4B 1975
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
100 HBA1 3039
Affinity Capture-MS Homo sapiens
101 ITPA 3704
Affinity Capture-MS Homo sapiens
102 CLTA 1211
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
103 CNGA3  
Negative Genetic Homo sapiens
104 CNTF  
Affinity Capture-MS Homo sapiens
105 SOS2 6655
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
106 TOPAZ1  
Affinity Capture-MS Homo sapiens
107 ADGRE5 976
Negative Genetic Homo sapiens
108 NUP85 79902
Affinity Capture-MS Homo sapiens
109 PPP2R2A 5520
Affinity Capture-MS Homo sapiens
110 GABPA 2551
Negative Genetic Homo sapiens
111 SNX29  
Affinity Capture-MS Homo sapiens
112 PCYT1A 5130
Negative Genetic Homo sapiens
113 SCAMP3 10067
Affinity Capture-MS Homo sapiens
114 SKA2  
Negative Genetic Homo sapiens
115 CTNND1 1500
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
116 PSMD3 5709
Negative Genetic Homo sapiens
117 AFG3L2 10939
Affinity Capture-MS Homo sapiens
118 ARMC5 79798
Negative Genetic Homo sapiens
119 PTPN22  
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
120 PPIE 10450
Negative Genetic Homo sapiens
121 CTBP2 1488
Affinity Capture-MS Homo sapiens
122 BTF3 689
Negative Genetic Homo sapiens
123 MTPAP 55149
Negative Genetic Homo sapiens
124 USP39 10713
Negative Genetic Homo sapiens
125 SHFM1 7979
Negative Genetic Homo sapiens
126 RNF8  
Negative Genetic Homo sapiens
127 URB2  
Negative Genetic Homo sapiens
128 SNRPF 6636
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
129 RPS3 6188
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
130 BTBD18  
Affinity Capture-MS Homo sapiens
131 RGS16 6004
Affinity Capture-Western Homo sapiens
132 USO1 8615
Negative Genetic Homo sapiens
133 SGPL1 8879
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 DDX24 57062
Negative Genetic Homo sapiens
135 H1FX 8971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 COPS6 10980
Negative Genetic Homo sapiens
137 HARS2 23438
Negative Genetic Homo sapiens
138 OSBP 5007
Affinity Capture-MS Homo sapiens
139 ACTR1A 10121
Negative Genetic Homo sapiens
140 NUP93 9688
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 WASH1 100287171
Negative Genetic Homo sapiens
142 RWDD1 51389
Affinity Capture-MS Homo sapiens
143 ABCD3 5825
Affinity Capture-MS Homo sapiens
144 POTEB  
Negative Genetic Homo sapiens
145 MED31  
Negative Genetic Homo sapiens
146 C5orf28  
Affinity Capture-MS Homo sapiens
147 PPIAL4F 728945
Negative Genetic Homo sapiens
148 ZCRB1  
Negative Genetic Homo sapiens
149 YWHAB 7529
Two-hybrid Homo sapiens
PCA Homo sapiens
150 TGIF1  
Negative Genetic Homo sapiens
151 PFKM 5213
Affinity Capture-MS Homo sapiens
152 IPO11 51194
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
153 SYMPK 8189
Negative Genetic Homo sapiens
154 PPP5C 5536
PCA Homo sapiens
155 NDFIP2 54602
Affinity Capture-Western Homo sapiens
156 PLSCR1 5359
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
157 MRPL45 84311
Negative Genetic Homo sapiens
158 PKN2 5586
Negative Genetic Homo sapiens
159 MOB4 25843
PCA Homo sapiens
160 RPL4 6124
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
161 LYN 4067
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Reconstituted Complex Homo sapiens
162 PRKAG1 5571
Affinity Capture-MS Homo sapiens
163 KRTAP16-1  
Affinity Capture-MS Homo sapiens
164 HAUS8  
Negative Genetic Homo sapiens
165 POLDIP2 26073
Affinity Capture-MS Homo sapiens
166 USP17L27  
Negative Genetic Homo sapiens
167 PATE1  
Affinity Capture-MS Homo sapiens
168 GEMIN7  
Negative Genetic Homo sapiens
169 RPLP0 6175
Negative Genetic Homo sapiens
170 RNF125  
Affinity Capture-MS Homo sapiens
171 RAPGEF1 2889
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
172 COG5 10466
Affinity Capture-MS Homo sapiens
173 TIMELESS  
Negative Genetic Homo sapiens
174 HAUS7  
Negative Genetic Homo sapiens
175 CDIPT 10423
Affinity Capture-MS Homo sapiens
176 TPX2  
Negative Genetic Homo sapiens
177 CHMP3 51652
Negative Genetic Homo sapiens
178 AGAP4  
Negative Genetic Homo sapiens
179 ACLY 47
Negative Genetic Homo sapiens
180 DEFA1 1667
Affinity Capture-MS Homo sapiens
181 ICAM1 3383
Affinity Capture-MS Homo sapiens
182 XPO1 7514
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
183 TPK1  
Negative Genetic Homo sapiens
184 CAV2 858
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
185 KIAA1524 57650
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
186 SNF8 11267
Negative Genetic Homo sapiens
187 UBL5 59286
Negative Genetic Homo sapiens
188 WAPAL  
Negative Genetic Homo sapiens
189 RPS27 6232
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
190 HAUS5 23354
Negative Genetic Homo sapiens
191 MAP2K3 5606
Affinity Capture-MS Homo sapiens
192 CDC45  
Negative Genetic Homo sapiens
193 JAK1 3716
Affinity Capture-MS Homo sapiens
194 SLC3A2 6520
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 FBXO2 26232
Affinity Capture-MS Homo sapiens
196 HIP1 3092
Affinity Capture-Western Homo sapiens
197 RHOB 388
Proximity Label-MS Homo sapiens
198 RPS18 6222
Negative Genetic Homo sapiens
199 ARGLU1  
Negative Genetic Homo sapiens
200 RAB3A 5864
PCA Homo sapiens
201 MCM3AP  
Negative Genetic Homo sapiens
202 CBWD1 55871
Negative Genetic Homo sapiens
203 LARP4 113251
Affinity Capture-MS Homo sapiens
204 HUWE1 10075
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
205 PHGDH 26227
Affinity Capture-MS Homo sapiens
206 CBLC  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
207 AP3S1 1176
Affinity Capture-MS Homo sapiens
208 CLPP 8192
Affinity Capture-MS Homo sapiens
209 TAF6 6878
Negative Genetic Homo sapiens
210 GIGYF2 26058
Affinity Capture-MS Homo sapiens
211 GRN 2896
Affinity Capture-MS Homo sapiens
212 TERF2  
Negative Genetic Homo sapiens
213 SLC35B1 10237
Negative Genetic Homo sapiens
214 TRAPPC5 126003
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
215 ILF3 3609
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
216 MAX  
Negative Genetic Homo sapiens
217 PEX19 5824
Affinity Capture-MS Homo sapiens
218 SSRP1 6749
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
219 CALU 813
Co-fractionation Homo sapiens
220 SF3B4 10262
Negative Genetic Homo sapiens
221 XPR1 9213
Negative Genetic Homo sapiens
222 KEAP1 9817
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Negative Genetic Homo sapiens
223 RPS4X 6191
Negative Genetic Homo sapiens
224 SOS1 6654
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
225 FKBP4 2288
PCA Homo sapiens
226 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
227 TOR1AIP1 26092
Affinity Capture-MS Homo sapiens
228 BUB3 9184
Affinity Capture-MS Homo sapiens
229 CDK1 983
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
230 RAD50 10111
Negative Genetic Homo sapiens
231 RPS26 6231
Negative Genetic Homo sapiens
232 IDH2 3418
Affinity Capture-MS Homo sapiens
233 SPAG7  
Affinity Capture-MS Homo sapiens
234 RIOK2 55781
Affinity Capture-MS Homo sapiens
235 CGRRF1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
236 DHX38 9785
Affinity Capture-MS Homo sapiens
237 DDX28  
Negative Genetic Homo sapiens
238 ATP1A1 476
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 GOT1 2805
PCA Homo sapiens
240 YKT6 10652
Negative Genetic Homo sapiens
241 CISH  
Protein-peptide Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
242 TCOF1 6949
Affinity Capture-MS Homo sapiens
243 QRSL1  
Negative Genetic Homo sapiens
244 AP3D1 8943
Affinity Capture-MS Homo sapiens
245 DBR1  
Affinity Capture-MS Homo sapiens
246 PRKRIR  
Negative Genetic Homo sapiens
247 CUL4A 8451
Affinity Capture-MS Homo sapiens
248 TRAIP  
Negative Genetic Homo sapiens
249 AP2S1 1175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
250 OTOP2  
Negative Genetic Homo sapiens
251 DHCR24 1718
Affinity Capture-MS Homo sapiens
252 TAF6L 10629
Negative Genetic Homo sapiens
253 PFKP 5214
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
254 EPS15 2060
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
255 APBA3  
Protein-peptide Homo sapiens
256 NABP2  
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
257 UQCRB 7381
Negative Genetic Homo sapiens
258 SSB 6741
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
259 GATB  
Negative Genetic Homo sapiens
260 PTPN1 5770
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Reconstituted Complex Homo sapiens
261 HOOK2  
Affinity Capture-MS Homo sapiens
262 LTN1 26046
Affinity Capture-MS Homo sapiens
263 INTS8  
Negative Genetic Homo sapiens
264 DIMT1 27292
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
265 RPAIN  
Negative Genetic Homo sapiens
266 RPL10A 4736
Negative Genetic Homo sapiens
267 PSMG3 84262
Negative Genetic Homo sapiens
268 TRIM28 10155
Affinity Capture-MS Homo sapiens
269 CLU 1191
Affinity Capture-MS Homo sapiens
270 SDHB 6390
Negative Genetic Homo sapiens
271 YARS2  
Negative Genetic Homo sapiens
272 SF3A2 8175
Negative Genetic Homo sapiens
273 SRP14 6727
Negative Genetic Homo sapiens
274 CCDC47 57003
Affinity Capture-MS Homo sapiens
275 UFSP2 55325
Negative Genetic Homo sapiens
276 ALCAM 214
Affinity Capture-MS Homo sapiens
277 GTF3A 2971
Negative Genetic Homo sapiens
278 PTGDS  
PCA Homo sapiens
279 CGB2  
Negative Genetic Homo sapiens
280 RBM8A 9939
Negative Genetic Homo sapiens
281 HSPA8 3312
PCA Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
282 ALAS1  
Negative Genetic Homo sapiens
283 ATAD3B 83858
Affinity Capture-MS Homo sapiens
284 PTEN 5728
Affinity Capture-Western Homo sapiens
285 AKAP12 9590
PCA Homo sapiens
286 GOLGA8J  
Negative Genetic Homo sapiens
287 TRMT61A 115708
Negative Genetic Homo sapiens
288 RPL9 6133
Negative Genetic Homo sapiens
289 CTU2 348180
Negative Genetic Homo sapiens
290 CXADR 1525
Proximity Label-MS Homo sapiens
291 KCTD9P2  
PCA Homo sapiens
292 CHCHD3 54927
Affinity Capture-MS Homo sapiens
293 TUBA1A 7846
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
294 NELL1  
Affinity Capture-MS Homo sapiens
295 FNTB 2342
Negative Genetic Homo sapiens
296 ACACA 31
Affinity Capture-MS Homo sapiens
297 OR2W3  
Affinity Capture-MS Homo sapiens
298 CYS1 192668
Affinity Capture-MS Homo sapiens
299 TUBA1B 10376
Negative Genetic Homo sapiens
300 CNOT1 23019
Negative Genetic Homo sapiens
301 BARD1 580
Negative Genetic Homo sapiens
302 RAE1 8480
Negative Genetic Homo sapiens
303 BCL2L2-PABPN1  
Negative Genetic Homo sapiens
304 IK 3550
Negative Genetic Homo sapiens
305 ARNT 405
Negative Genetic Homo sapiens
306 ANKRD13B  
Affinity Capture-Western Homo sapiens
307 KPNB1 3837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
308 AAMDC  
Affinity Capture-MS Homo sapiens
309 TRUB2  
Negative Genetic Homo sapiens
310 TECR 9524
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
311 PELP1 27043
Negative Genetic Homo sapiens
312 AGAP5  
Negative Genetic Homo sapiens
313 DNM1L 10059
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
314 EIF2B4 8890
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
315 SF3A3 10946
Negative Genetic Homo sapiens
316 TAF13  
Negative Genetic Homo sapiens
317 KIF18A  
Negative Genetic Homo sapiens
318 HTR3A  
Affinity Capture-MS Homo sapiens
319 RBBP6 5930
Negative Genetic Homo sapiens
320 SF3B2 10992
Negative Genetic Homo sapiens
321 KATNBL1  
Affinity Capture-MS Homo sapiens
322 EMC6 83460
Negative Genetic Homo sapiens
323 TRMT10C 54931
Affinity Capture-MS Homo sapiens
324 KIAA1244  
Affinity Capture-MS Homo sapiens
325 ECT2 1894
Negative Genetic Homo sapiens
326 HN1 51155
Affinity Capture-MS Homo sapiens
327 HRNR 388697
Affinity Capture-MS Homo sapiens
328 OLFM1  
PCA Homo sapiens
329 ZC3H8  
Negative Genetic Homo sapiens
330 ATXN10 25814
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
331 GBF1 8729
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
332 ACE2 59272
Affinity Capture-MS Homo sapiens
333 C10orf10  
Negative Genetic Homo sapiens
334 TM9SF3 56889
Affinity Capture-MS Homo sapiens
335 NCAPH 23397
Affinity Capture-MS Homo sapiens
336 MYO1D 4642
Affinity Capture-MS Homo sapiens
337 PRPF19 27339
Negative Genetic Homo sapiens
338 HJURP  
Negative Genetic Homo sapiens
339 RPS13 6207
Negative Genetic Homo sapiens
340 EXOSC3 51010
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
341 NEK8  
Affinity Capture-MS Homo sapiens
342 INO80  
Negative Genetic Homo sapiens
343 TOP1 7150
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
344 RPL12 6136
Negative Genetic Homo sapiens
345 SKIV2L2 23517
Negative Genetic Homo sapiens
346 RAF1 5894
Two-hybrid Homo sapiens
PCA Homo sapiens
347 RANBP1 5902
Affinity Capture-MS Homo sapiens
348 KIAA0368 23392
Affinity Capture-MS Homo sapiens
349 NARFL 64428
Negative Genetic Homo sapiens
350 PRPF18  
Negative Genetic Homo sapiens
351 NEDD4L 23327
Affinity Capture-Western Homo sapiens
352 NAA10 8260
Affinity Capture-MS Homo sapiens
353 SNRPD2 6633
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
354 DRD2  
Affinity Capture-MS Homo sapiens
355 C3orf17  
Negative Genetic Homo sapiens
356 ZNF574  
Negative Genetic Homo sapiens
357 MECR 51102
Negative Genetic Homo sapiens
358 HERC1 8925
Affinity Capture-MS Homo sapiens
359 AHSA1 10598
PCA Homo sapiens
360 GPR89A  
Negative Genetic Homo sapiens
361 SOD2 6648
Negative Genetic Homo sapiens
362 MAP2K4 6416
Affinity Capture-MS Homo sapiens
363 VPS28 51160
Negative Genetic Homo sapiens
364 MTBP  
Affinity Capture-MS Homo sapiens
365 RPTOR 57521
Negative Genetic Homo sapiens
366 CAP2 10486
Affinity Capture-MS Homo sapiens
367 AFF3  
Negative Genetic Homo sapiens
368 WAS 7454
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
369 NLRP10  
Affinity Capture-MS Homo sapiens
370 SFTPC  
Affinity Capture-MS Homo sapiens
371 LTK 4058
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
372 UFL1 23376
Affinity Capture-MS Homo sapiens
373 NF1 4763
Affinity Capture-MS Homo sapiens
374 TBRG4 9238
Affinity Capture-MS Homo sapiens
375 SRRD  
Negative Genetic Homo sapiens
376 TRIM23 373
Affinity Capture-MS Homo sapiens
377 NEDD1 121441
Negative Genetic Homo sapiens
378 AASDH  
Affinity Capture-MS Homo sapiens
379 RPRD1B 58490
Negative Genetic Homo sapiens
380 EZR 7430
PCA Homo sapiens
381 SNX2 6643
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
382 CD44 960
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
383 COPS4 51138
Negative Genetic Homo sapiens
384 NUCKS1 64710
Affinity Capture-MS Homo sapiens
385 VPS72  
Negative Genetic Homo sapiens
386 UBE2V2 7336
PCA Homo sapiens
387 LUC7L3 51747
Affinity Capture-MS Homo sapiens
388 PCDHB3  
Affinity Capture-MS Homo sapiens
389 ACTR2 10097
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
390 HEATR4  
Affinity Capture-MS Homo sapiens
391 AP2B1 163
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
392 RPS3A 6189
Negative Genetic Homo sapiens
393 CSK 1445
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
394 BCLAF1 9774
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
395 SLC45A2 51151
Affinity Capture-MS Homo sapiens
396 CT47A6  
Negative Genetic Homo sapiens
397 CTDNEP1 23399
Negative Genetic Homo sapiens
398 NUPL1 9818
Negative Genetic Homo sapiens
399 MRPL52  
Negative Genetic Homo sapiens
400 CFL1 1072
PCA Homo sapiens
Negative Genetic Homo sapiens
401 TFAP2C 7022
Negative Genetic Homo sapiens
402 TAF5  
Negative Genetic Homo sapiens
403 TOMM22 56993
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
404 RNH1 6050
Negative Genetic Homo sapiens
405 RPS20 6224
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
406 PLCG2 5336
Protein-peptide Homo sapiens
Two-hybrid Homo sapiens
Co-localization Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Reconstituted Complex Homo sapiens
407 TFAM 7019
Negative Genetic Homo sapiens
408 PCID2 55795
Negative Genetic Homo sapiens
409 AKIRIN2  
Negative Genetic Homo sapiens
410 Cbl  
Affinity Capture-Western Drosophila melanogaster
Affinity Capture-Western Drosophila melanogaster
411 YES1 7525
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
412 MDH1 4190
PCA Homo sapiens
413 SNRPC 6631
Negative Genetic Homo sapiens
414 SOCS5  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
415 TEKT2  
Affinity Capture-MS Homo sapiens
416 TEAD1  
Negative Genetic Homo sapiens
417 RAD51  
Negative Genetic Homo sapiens
418 SHC4  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Reconstituted Complex Homo sapiens
419 RPS10-NUDT3 100529239
Negative Genetic Homo sapiens
420 Cbl 12402
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
421 ZBTB8OS 339487
Negative Genetic Homo sapiens
422 DNAH7 56171
Affinity Capture-MS Homo sapiens
423 ATP5H 10476
Negative Genetic Homo sapiens
424 TMEM2 23670
Affinity Capture-MS Homo sapiens
425 WDR1 9948
Negative Genetic Homo sapiens
426 PET100  
Negative Genetic Homo sapiens
427 MRPS30 10884
Negative Genetic Homo sapiens
428 PDK1 5163
Affinity Capture-MS Homo sapiens
429 PPIB 5479
Affinity Capture-MS Homo sapiens
430 HCK 3055
Two-hybrid Homo sapiens
PCA Homo sapiens
Co-localization Homo sapiens
431 DPP4 1803
Affinity Capture-MS Homo sapiens
432 SFXN3 81855
Affinity Capture-MS Homo sapiens
433 NEURL2  
Negative Genetic Homo sapiens
434 CCT5 22948
Negative Genetic Homo sapiens
435 MAPK8IP1 9479
Protein-peptide Homo sapiens
436 UBE2I 7329
Negative Genetic Homo sapiens
437 LOC100144595  
Negative Genetic Homo sapiens
438 DDX5 1655
Affinity Capture-MS Homo sapiens
439 TRIT1  
Negative Genetic Homo sapiens
440 GANAB 23193
Negative Genetic Homo sapiens
441 PML 5371
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
442 BRAF  
Negative Genetic Homo sapiens
443 ATP2B4 493
Affinity Capture-MS Homo sapiens
444 PAGE3  
Affinity Capture-MS Homo sapiens
445 ITCH 83737
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
446 MRPL14 64928
Negative Genetic Homo sapiens
447 SLC7A1 6541
Negative Genetic Homo sapiens
448 SMARCC2 6601
Negative Genetic Homo sapiens
449 WDR82 80335
Negative Genetic Homo sapiens
450 MBTPS1 8720
Negative Genetic Homo sapiens
451 DDX59 83479
Negative Genetic Homo sapiens
452 PRX 57716
Negative Genetic Homo sapiens
453 FGD5  
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
454 UBE2N 7334
Negative Genetic Homo sapiens
455 SFPQ 6421
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
456 IPO5 3843
Affinity Capture-MS Homo sapiens
457 RPLP2 6181
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
458 RPL7A 6130
Negative Genetic Homo sapiens
459 NDUFA9 4704
Affinity Capture-MS Homo sapiens
460 PSMD13 5719
Negative Genetic Homo sapiens
461 LETM1 3954
Negative Genetic Homo sapiens
462 RPL35 11224
Negative Genetic Homo sapiens
463 SH2D1B  
Reconstituted Complex Homo sapiens
464 LAMP1 3916
Co-localization Homo sapiens
465 Bmpr1a  
Affinity Capture-MS Mus musculus
466 HCFC1 3054
Affinity Capture-MS Homo sapiens
467 MIPEP  
Negative Genetic Homo sapiens
468 XAB2 56949
Negative Genetic Homo sapiens
469 ANKRD13D  
Affinity Capture-Western Homo sapiens
470 CNPY3 10695
Affinity Capture-MS Homo sapiens
471 RPP30 10556
Negative Genetic Homo sapiens
472 PPIAL4C 653598
Negative Genetic Homo sapiens
473 TBCD 6904
Negative Genetic Homo sapiens
474 SF3A1 10291
Negative Genetic Homo sapiens
475 TRPV1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
476 DIS3 22894
Affinity Capture-MS Homo sapiens
477 DAZL  
Affinity Capture-MS Homo sapiens
478 EPN1 29924
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
479 ZFYVE21  
Affinity Capture-MS Homo sapiens
480 EEF1B2 1933
Affinity Capture-MS Homo sapiens
481 DYRK2 8445
Negative Genetic Homo sapiens
482 CHD8 57680
Negative Genetic Homo sapiens
483 RPIA 22934
Negative Genetic Homo sapiens
484 ATP5C1 509
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
485 PTPRU  
Biochemical Activity Homo sapiens
486 C11orf84  
Affinity Capture-MS Homo sapiens
487 DUSP18  
Affinity Capture-Western Homo sapiens
488 THADA 63892
Affinity Capture-MS Homo sapiens
489 NOL6 65083
Affinity Capture-MS Homo sapiens
490 EFCAB3 146779
Affinity Capture-MS Homo sapiens
491 DNAJC13 23317
Affinity Capture-MS Homo sapiens
492 MYO1C 4641
Affinity Capture-MS Homo sapiens
493 TNK2 10188
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
494 ACP1 52
Affinity Capture-MS Homo sapiens
495 ADAT3 113179
Negative Genetic Homo sapiens
496 PDE4C  
Negative Genetic Homo sapiens
497 EHD4 30844
Affinity Capture-MS Homo sapiens
498 SSU72 29101
Negative Genetic Homo sapiens
499 INPPL1 3636
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
500 STRAP 11171
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
501 PRR19  
Negative Genetic Homo sapiens
502 CCDC146  
Affinity Capture-MS Homo sapiens
503 DUSP3 1845
Biochemical Activity Homo sapiens
504 Syngap1  
Affinity Capture-Western Mus musculus
505 MRPL43 84545
Affinity Capture-MS Homo sapiens
506 SUCLA2 8803
Affinity Capture-MS Homo sapiens
507 EPB41L2 2037
Affinity Capture-MS Homo sapiens
508 PRR12 57479
Negative Genetic Homo sapiens
509 MTERF4  
Negative Genetic Homo sapiens
510 FADS2 9415
Affinity Capture-MS Homo sapiens
511 ITSN2 50618
Two-hybrid Homo sapiens
PCA Homo sapiens
512 DHX16 8449
Affinity Capture-MS Homo sapiens
513 BRICD5  
Affinity Capture-MS Homo sapiens
514 GTF2H3  
Negative Genetic Homo sapiens
515 PHLDA1 22822
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
516 RPL23 9349
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
517 MTG1  
Affinity Capture-MS Homo sapiens
518 IPO13 9670
Affinity Capture-MS Homo sapiens
519 GNB2L1 10399
Negative Genetic Homo sapiens
520 HECW2  
Affinity Capture-MS Homo sapiens
521 CRCT1  
Affinity Capture-MS Homo sapiens
522 ARHGAP1 392
Affinity Capture-MS Homo sapiens
523 WDR6 11180
Affinity Capture-MS Homo sapiens
524 LAIR2  
Negative Genetic Homo sapiens
525 UTP11L  
Negative Genetic Homo sapiens
526 RCL1 10171
Negative Genetic Homo sapiens
527 CDH5  
Two-hybrid Homo sapiens
PCA Homo sapiens
528 GPATCH8  
Affinity Capture-MS Homo sapiens
529 LIMS1 3987
Negative Genetic Homo sapiens
530 CD300LB  
Affinity Capture-MS Homo sapiens
531 BRD2  
Co-localization Homo sapiens
532 RBM41  
Affinity Capture-MS Homo sapiens
533 CSTA 1475
Affinity Capture-MS Homo sapiens
534 RIPK1 8737
Affinity Capture-Western Homo sapiens
535 RABGGTB 5876
Negative Genetic Homo sapiens
536 SHE  
Reconstituted Complex Homo sapiens
537 APEX1 328
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
538 SPDYE6  
Negative Genetic Homo sapiens
539 PELI1 57162
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
540 CHAF1A  
Negative Genetic Homo sapiens
541 MON2 23041
Affinity Capture-MS Homo sapiens
542 APBB2  
Protein-peptide Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
543 SPATA5 166378
Negative Genetic Homo sapiens
544 DUSP14 11072
Affinity Capture-Western Homo sapiens
545 TIMM23 100287932
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
546 DHDDS  
Negative Genetic Homo sapiens
547 PIK3C3 5289
Negative Genetic Homo sapiens
548 LAMTOR3 8649
Negative Genetic Homo sapiens
549 SYS1  
Negative Genetic Homo sapiens
550 OCLN 100506658
Proximity Label-MS Homo sapiens
551 HERC2 8924
Affinity Capture-MS Homo sapiens
552 FBXO5  
Negative Genetic Homo sapiens
553 ZBTB14  
Affinity Capture-MS Homo sapiens
554 BRF2  
Negative Genetic Homo sapiens
555 RPS11 6205
Negative Genetic Homo sapiens
556 RPL19 6143
Negative Genetic Homo sapiens
557 RGS4  
Two-hybrid Homo sapiens
PCA Homo sapiens
558 BAG5 9529
Affinity Capture-MS Homo sapiens
559 TEC 7006
Reconstituted Complex Homo sapiens
560 TXNL4B  
Negative Genetic Homo sapiens
561 SBNO1 55206
Negative Genetic Homo sapiens
562 SORBS2  
PCA Homo sapiens
563 CENPL  
Affinity Capture-MS Homo sapiens
564 CALM1  
Reconstituted Complex Bos taurus
565 NT5DC2 64943
Affinity Capture-MS Homo sapiens
566 PRKCG 5582
Negative Genetic Homo sapiens
567 EREG  
Affinity Capture-Luminescence Homo sapiens
568 SH2B2  
Reconstituted Complex Homo sapiens
569 UBASH3B 84959
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
570 CIRH1A 84916
Negative Genetic Homo sapiens
571 CDH1 999
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Co-localization Homo sapiens
PCA Homo sapiens
Affinity Capture-MS Homo sapiens
572 UBA3 9039
Negative Genetic Homo sapiens
573 SH2D1A 4068
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
574 ACTN4 81
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
575 DTX2 113878
Proximity Label-MS Homo sapiens
576 C6orf120  
Affinity Capture-MS Homo sapiens
577 XPOT 11260
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
578 P4HB 5034
Affinity Capture-MS Homo sapiens
579 THG1L 54974
Negative Genetic Homo sapiens
580 EIF1AY 9086
Affinity Capture-MS Homo sapiens
581 ZNF581  
Negative Genetic Homo sapiens
582 ZRSR2  
Negative Genetic Homo sapiens
583 C19orf35  
Affinity Capture-Western Homo sapiens
584 PRKAR1B  
PCA Homo sapiens
585 MAPK8 5599
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
586 VPS18 57617
Negative Genetic Homo sapiens
587 BIRC2  
Affinity Capture-Western Homo sapiens
588 ZBTB17  
Negative Genetic Homo sapiens
589 SPRR1A  
Affinity Capture-MS Homo sapiens
590 SOCS2  
Reconstituted Complex Homo sapiens
591 NBAS 51594
Negative Genetic Homo sapiens
592 FAM129B 64855
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
593 ABT1 29777
Negative Genetic Homo sapiens
594 MRTO4 51154
Affinity Capture-MS Homo sapiens
595 NUBP2 10101
Affinity Capture-MS Homo sapiens
596 TEKT4  
Negative Genetic Homo sapiens
597 RQCD1 9125
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Negative Genetic Homo sapiens
598 C19orf66  
Negative Genetic Homo sapiens
599 TNFRSF1A 7132
Two-hybrid Homo sapiens
PCA Homo sapiens
600 CUL3 8452
Negative Genetic Homo sapiens
601 ERBB4 2066
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
602 FKBP8 23770
PCA Homo sapiens
603 TTF2 8458
Negative Genetic Homo sapiens
604 TP53TG3C  
Negative Genetic Homo sapiens
605 GTF3C4 9329
Negative Genetic Homo sapiens
606 COL1A1 1277
Affinity Capture-MS Homo sapiens
607 WDR43 23160
Negative Genetic Homo sapiens
608 GOLGA6L6  
Negative Genetic Homo sapiens
609 CGB  
Negative Genetic Homo sapiens
610 UBA2 10054
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
611 MFAP1  
Affinity Capture-MS Homo sapiens
612 RET 5979
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Western Homo sapiens
613 WRB 7485
Negative Genetic Homo sapiens
614 COX6C 1345
Negative Genetic Homo sapiens
615 FAM66E  
Affinity Capture-MS Homo sapiens
616 TBCA 6902
Negative Genetic Homo sapiens
617 CTNNA1 1495
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
618 NPHP4 261734
Affinity Capture-MS Homo sapiens
619 INTS5 80789
Negative Genetic Homo sapiens
620 TPM4 7171
Affinity Capture-MS Homo sapiens
621 UROD 7389
PCA Homo sapiens
Negative Genetic Homo sapiens
622 DUSP19  
Two-hybrid Homo sapiens
623 WDR77 79084
Negative Genetic Homo sapiens
624 POLR2J  
Negative Genetic Homo sapiens
625 SSH1  
Affinity Capture-Western Homo sapiens
626 RBM25 58517
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
627 FCGRT 2217
Negative Genetic Homo sapiens
628 SULT1A1 6817
Affinity Capture-MS Homo sapiens
629 EMC7 56851
Negative Genetic Homo sapiens
630 CD1B 910
Affinity Capture-MS Homo sapiens
631 KAT7  
Negative Genetic Homo sapiens
632 LCK 3932
Reconstituted Complex Homo sapiens
633 WRAP53  
Negative Genetic Homo sapiens
634 RGPD8  
Negative Genetic Homo sapiens
635 TKT 7086
Negative Genetic Homo sapiens
636 PUF60 22827
Negative Genetic Homo sapiens
637 PRPF31 26121
Negative Genetic Homo sapiens
638 SUGP2  
Affinity Capture-MS Homo sapiens
639 OAT 4942
Affinity Capture-MS Homo sapiens
640 DYNC1H1 1778
PCA Homo sapiens
641 COL1A2 1278
Affinity Capture-MS Homo sapiens
642 XPO5 57510
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
643 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
644 HNRNPL 3191
Negative Genetic Homo sapiens
645 SUPT6H 6830
Reconstituted Complex Homo sapiens
Negative Genetic Homo sapiens
646 ACACB 32
Affinity Capture-MS Homo sapiens
647 PGM3 5238
Negative Genetic Homo sapiens
648 TXNIP 10628
Affinity Capture-Western Homo sapiens
649 SMURF2 64750
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
650 SLCO3A1 28232
Affinity Capture-MS Homo sapiens
651 POLG  
Negative Genetic Homo sapiens
652 NTRK2 4915
Two-hybrid Homo sapiens
PCA Homo sapiens
653 SNRPA1 6627
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
654 PTCH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
655 NOP10 55505
Negative Genetic Homo sapiens
656 NDN 4692
PCA Homo sapiens
657 IMP4  
Negative Genetic Homo sapiens
658 WWC2  
Affinity Capture-MS Homo sapiens
659 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
660 PTPRF 5792
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
661 FAM98A 25940
Affinity Capture-MS Homo sapiens
662 TMEM145  
Negative Genetic Homo sapiens
663 TRRAP 8295
Negative Genetic Homo sapiens
664 SCGB1D4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
665 APRT 353
Affinity Capture-MS Homo sapiens
666 UCHL1 7345
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
667 PHOSPHO1  
Negative Genetic Homo sapiens
668 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
669 GRB10 2887
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
670 HOXC10  
Affinity Capture-MS Homo sapiens
671 SRSF2 6427
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
672 PPP2R1B 5519
Affinity Capture-MS Homo sapiens
673 AKAP17A  
Affinity Capture-MS Homo sapiens
674 HOXC13  
Negative Genetic Homo sapiens
675 NOLC1 9221
Negative Genetic Homo sapiens
676 MUC1 4582
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
677 TNIK 23043
Affinity Capture-MS Homo sapiens
678 PPP6R1 22870
Affinity Capture-MS Homo sapiens
679 MAPK14 1432
Biochemical Activity Homo sapiens
Co-localization Homo sapiens
680 FER 2241
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
681 TINF2  
Negative Genetic Homo sapiens
682 STIP1 10963
PCA Homo sapiens
683 TMEM97 27346
Affinity Capture-MS Homo sapiens
684 BIRC3 330
Affinity Capture-Western Homo sapiens
685 L1CAM 3897
Affinity Capture-Western Homo sapiens
686 AKTIP  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
687 PSMA1 5682
Negative Genetic Homo sapiens
688 ACTA2 59
Affinity Capture-MS Homo sapiens
689 STAM2 10254
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
690 NAE1 8883
Negative Genetic Homo sapiens
691 SLC1A5 6510
Affinity Capture-MS Homo sapiens
692 KRTAP15-1  
Affinity Capture-MS Homo sapiens
693 RBX1 9978
Negative Genetic Homo sapiens
694 VPS45 11311
Negative Genetic Homo sapiens
695 STOM 2040
Affinity Capture-MS Homo sapiens
696 PSMD14 10213
Negative Genetic Homo sapiens
697 RNF115  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
698 RCC2 55920
Affinity Capture-MS Homo sapiens
699 POLR3F  
Negative Genetic Homo sapiens
700 VRK1 7443
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
701 TNC 3371
Affinity Capture-MS Homo sapiens
702 PSMD8 5714
Negative Genetic Homo sapiens
703 EXOSC5 56915
Negative Genetic Homo sapiens
704 RLIM 51132
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
705 PPP2CA 5515
Negative Genetic Homo sapiens
706 GAPDH 2597
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
707 UQCRC1 7384
Negative Genetic Homo sapiens
708 LRRTM4  
Affinity Capture-MS Homo sapiens
709 CYLD  
Affinity Capture-Western Homo sapiens
710 SUCO  
Negative Genetic Homo sapiens
711 OSCAR  
Negative Genetic Homo sapiens
712 LAT 27040
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
713 RPL32 6161
Negative Genetic Homo sapiens
714 PSMA3 5684
Affinity Capture-MS Homo sapiens
715 SUSD1 64420
Affinity Capture-MS Homo sapiens
716 ANO5  
Affinity Capture-MS Homo sapiens
717 AIFM1 9131
Affinity Capture-MS Homo sapiens
718 RPS2 6187
Negative Genetic Homo sapiens
719 ILKAP 80895
Two-hybrid Homo sapiens
720 SEC13 6396
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
721 GABRA3  
Affinity Capture-MS Homo sapiens
722 GPR89B 51463
Negative Genetic Homo sapiens
723 CTTN 2017
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
724 TUBB4B 10383
Affinity Capture-MS Homo sapiens
725 ERCC4  
Affinity Capture-MS Homo sapiens
726 EGFR 1956
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
FRET Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
PCA Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Co-purification Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Negative Genetic Homo sapiens
PCA Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
FRET Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
PCA Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Co-purification Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Negative Genetic Homo sapiens
PCA Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
727 HSD17B10 3028
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
728 BRD3 8019
Co-localization Homo sapiens
729 FUS 2521
Affinity Capture-MS Homo sapiens
730 KBTBD7  
Affinity Capture-MS Homo sapiens
731 GAB1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Biochemical Activity Homo sapiens