Gene description for Cd40lg
Gene name	CD40 ligand
Gene symbol	Cd40lg
Other names/aliases	CD154 CD40-L Cd40l HIGM1 IGM IMD3 Ly-62 Ly62 T-BAM TRAP Tnfsf5 gp39
Species	Mus musculus
Database cross references - Cd40lg
ExoCarta	ExoCarta_21947
Entrez Gene	21947
UniProt	P27548
Cd40lg identified in exosomes derived from the following tissue/cell type
Mast cells	11145662

Gene ontology annotations for Cd40lg

Molecular Function     tumor necrosis factor receptor binding GO:0005164 IEA     CD40 receptor binding GO:0005174 ISO     cytokine activity GO:0005125 IEA Biological Process     negative regulation of apoptotic process GO:0043066 ISO     positive regulation of interleukin-10 production GO:0032733 ISO     immune response GO:0006955 IEA     positive regulation of endothelial cell apoptotic process GO:2000353 ISO     isotype switching GO:0045190 IDA     immunoglobulin secretion GO:0048305 IGI     positive regulation of interleukin-12 production GO:0032735 ISO     B cell differentiation GO:0030183 IGI     regulation of immunoglobulin secretion GO:0051023 IDA     dendritic cell differentiation GO:0097028 ISO     signal transduction GO:0007165 NAS     platelet activation GO:0030168 ISO     B cell proliferation GO:0042100 ISO     inflammatory response GO:0006954 ISO     positive regulation of B cell proliferation GO:0030890 ISO     positive regulation of immune response to tumor cell GO:0002839 ISO     positive regulation of MHC class II biosynthetic process GO:0045348 ISO     positive regulation of interferon-gamma production GO:0032729 ISO Subcellular Localization     membrane GO:0016020 IEA     extracellular space GO:0005615 ISO     integral component of membrane GO:0016021 IEA     cell GO:0005623 IGI     external side of plasma membrane GO:0009897 IDA     plasma membrane GO:0005886 IEA     cell surface GO:0009986 ISO     extracellular region GO:0005576 IEA