Gene description for Slc39a10
Gene name solute carrier family 39 (zinc transporter), member 10
Gene symbol Slc39a10
Other names/aliases 2900042E17Rik
5430433I10
mKIAA1265
Species Mus musculus
 Database cross references - Slc39a10
ExoCarta ExoCarta_227059
Vesiclepedia VP_227059
Entrez Gene 227059
UniProt Q6P5F6  
 Slc39a10 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Slc39a10
Molecular Function
    molecular_function GO:0003674 ND
    metal ion transmembrane transporter activity GO:0046873 IEA
Biological Process
    ion transport GO:0006811 IEA
    zinc II ion transport GO:0006829 IEA
    transport GO:0006810 IEA
    biological_process GO:0008150 ND
    metal ion transport GO:0030001 IEA
    transmembrane transport GO:0055085 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    cellular_component GO:0005575 ND
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Slc39a10 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Slc39a10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc39a10 is involved
PathwayEvidenceSource
Zinc influx into cells by the SLC39 gene family IEA Reactome





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