Gene description for Cadm2
Gene name cell adhesion molecule 2
Gene symbol Cadm2
Other names/aliases 2900078E11Rik
9330131D06
A830029E02Rik
Igdf4d
Igsf4d
NECL3
SynCAM 2
SynCAM2
Species Mus musculus
 Database cross references - Cadm2
ExoCarta ExoCarta_239857
Entrez Gene 239857
UniProt Q8BLQ9  
 Cadm2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cadm2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cell adhesion GO:0007155 IEA
Subcellular Localization
    neuronal cell body membrane GO:0032809 ISO
    integral component of membrane GO:0016021 IEA
    cell junction GO:0030054 IEA
    membrane GO:0016020 IEA
    synapse GO:0045202 IEA
    cell projection GO:0042995 IEA
    cytoplasm GO:0005737 ISO
    plasma membrane GO:0005886 IEA
    axon GO:0030424 ISO
 Experiment description of studies that identified Cadm2 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cadm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cadm2 is involved
PathwayEvidenceSource
Adherens junctions interactions IEA Reactome





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