Gene description for Ctse
Gene name cathepsin E
Gene symbol Ctse
Other names/aliases CEA
CEB
Ctsea
Species Rattus norvegicus
 Database cross references - Ctse
ExoCarta ExoCarta_25424
Entrez Gene 25424
UniProt P16228  
 Ctse identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Ctse
Molecular Function
    aspartic-type endopeptidase activity GO:0004190 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    protein autoprocessing GO:0016540 IMP
    protein catabolic process GO:0030163 IBA
    proteolysis GO:0006508 ISO
    antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    endosome GO:0005768 ISO
 Experiment description of studies that identified Ctse in exosomes
1
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Ctse
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ctse is involved
No pathways found





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