Gene description for Fcer1g
Gene name Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
Gene symbol Fcer1g
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fcer1g
ExoCarta ExoCarta_25441
Entrez Gene 25441
UniProt P20411  
 Fcer1g identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Fcer1g
Molecular Function
    IgE receptor activity GO:0019767 ISO
    IgG binding GO:0019864 ISO
    IgE binding GO:0019863 ISO
Biological Process
    positive regulation of mast cell degranulation GO:0043306 ISO
    neutrophil chemotaxis GO:0030593 ISO
    innate immune response GO:0045087 ISO
    T cell differentiation involved in immune response GO:0002292 ISO
    Fc-gamma receptor signaling pathway GO:0038094 ISO
    Fc receptor mediated stimulatory signaling pathway GO:0002431 ISO
    phagocytosis, engulfment GO:0006911 ISO
    mast cell activation GO:0045576 ISO
    positive regulation of type IIa hypersensitivity GO:0001798 ISO
    positive regulation of interleukin-10 production GO:0032733 ISO
    positive regulation of type III hypersensitivity GO:0001805 ISO
    positive regulation of mast cell cytokine production GO:0032765 ISO
    negative regulation of mast cell apoptotic process GO:0033026 ISO
    positive regulation of type I hypersensitivity GO:0001812 ISO
    positive regulation of interleukin-6 production GO:0032755 ISO
    cell surface receptor signaling pathway GO:0007166 ISO
    integrin-mediated signaling pathway GO:0007229 ISO
    neutrophil activation involved in immune response GO:0002283 ISO
    regulation of immune response GO:0050776 ISO
    positive regulation of tumor necrosis factor production GO:0032760 ISO
    positive regulation of phagocytosis GO:0050766 ISO
    protein localization to plasma membrane GO:0072659 ISO
    Fc-epsilon receptor signaling pathway GO:0038095 ISO
    serotonin secretion by platelet GO:0002554 ISO
    defense response to bacterium GO:0042742 ISO
    regulation of platelet activation GO:0010543 ISO
    antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 ISO
    signal transduction GO:0007165 ISO
    positive regulation of immune response GO:0050778 ISO
    immunoglobulin mediated immune response GO:0016064 ISO
    antigen processing and presentation of exogenous peptide antigen via MHC class I GO:0042590 ISO
Subcellular Localization
    cell surface GO:0009986 ISO
    external side of plasma membrane GO:0009897 ISO
    Fc-epsilon receptor I complex GO:0032998 ISO
    integral component of plasma membrane GO:0005887 ISO
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Fcer1g in exosomes
1
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Fcer1g
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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