Gene description for Map2
Gene name microtubule-associated protein 2
Gene symbol Map2
Other names/aliases MAP2R
Mtap2
Species Rattus norvegicus
 Database cross references - Map2
ExoCarta ExoCarta_25595
Vesiclepedia VP_25595
Entrez Gene 25595
UniProt P15146  
 Map2 identified in exosomes derived from the following tissue/cell type
Plasma 34654817    
Plasma 34654817    
 Gene ontology annotations for Map2
Molecular Function
    microtubule binding GO:0008017 ISO
    protein binding GO:0005515 IPI
    dystroglycan binding GO:0002162 ISO
    calmodulin binding GO:0005516 IEA
Biological Process
    dendrite development GO:0016358 ISO
    microtubule bundle formation GO:0001578 ISO
    dendrite morphogenesis GO:0048813 ISO
    neuron projection development GO:0031175 ISO
    response to progesterone GO:0032570 IEP
    axonogenesis GO:0007409 ISO
    central nervous system neuron development GO:0021954 ISO
    cellular response to organic substance GO:0071310 ISO
    response to estradiol GO:0032355 IEP
Subcellular Localization
    rough endoplasmic reticulum GO:0005791 IDA
    neuronal cell body GO:0043025 ISO
    nuclear periphery GO:0034399 ISO
    cell body GO:0044297 ISO
    intracellular GO:0005622 ISO
    protein complex GO:0043234 IDA
    neuron projection GO:0043005 ISO
    smooth endoplasmic reticulum GO:0005790 IDA
    dendritic shaft GO:0043198 ISO
    postsynaptic density GO:0014069 ISO
    neuronal postsynaptic density GO:0097481 ISO
    nucleolus GO:0005730 ISO
    CA3 pyramidal cell dendrite GO:0097442 ISO
    microtubule GO:0005874 IEA
    cytoplasm GO:0005737 ISO
    dendrite GO:0030425 ISO
 Experiment description of studies that identified Map2 in exosomes
1
Experiment ID 1154
MISEV standards
EM
EV Biophysical techniques
Tsg101|Cd9|Cd63|Uchl1
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34654817    
Organism Rattus norvegicus
Experiment description Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors
Authors Xia W, Xie J, Cai Z, Liu X, Wen J, Cui ZK, Zhao R, Zhou X, Chen J, Mao X, Gu Z, Zou Z, Zou Z, Zhang Y, Zhao M, Mac M, Song Q, Bai X.
Journal name Nat Commun
Publication year 2021
Sample Plasma
Sample name Sham - Sprague-Dawley rat
Isolation/purification methods ExoQuick Kit
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
miRNA sequencing
qRT-PCR
Mass spectrometry
2
Experiment ID 1155
MISEV standards
EV Biophysical techniques
Tsg101|Cd9|Cd63|Uchl1
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34654817    
Organism Rattus norvegicus
Experiment description Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors
Authors Xia W, Xie J, Cai Z, Liu X, Wen J, Cui ZK, Zhao R, Zhou X, Chen J, Mao X, Gu Z, Zou Z, Zou Z, Zhang Y, Zhao M, Mac M, Song Q, Bai X.
Journal name Nat Commun
Publication year 2021
Sample Plasma
Sample name Post-traumatic brain injury surgery (24 h) - Sprague-Dawley rat
Isolation/purification methods ExoQuick Kit
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
miRNA sequencing
qRT-PCR
Mass spectrometry
 Protein-protein interactions for Map2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Map2 is involved
No pathways found





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