Gene description for MYO1C
Gene name myosin IC
Gene symbol MYO1C
Other names/aliases MMIb
Species Bos taurus
 Database cross references - MYO1C
ExoCarta ExoCarta_281937
Entrez Gene 281937
UniProt Q27966  
 MYO1C identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MYO1C
Molecular Function
    motor activity GO:0003774 IEA
    actin binding GO:0003779 IEA
    calmodulin binding GO:0005516 IEA
    ATP binding GO:0005524 IEA
    protein C-terminus binding GO:0008022 IEA
    Ral GTPase binding GO:0017160 IEA
    receptor binding GO:0005102 IEA
Biological Process
    positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 IEA
    positive regulation of cell migration by vascular endothelial growth factor signaling pathway GO:0038089 IEA
    positive regulation of protein targeting to membrane GO:0090314 IEA
    mRNA transport GO:0051028 IEA
    metabolic process GO:0008152 IEA
    protein targeting to membrane GO:0006612 IEA
    regulation of bicellular tight junction assembly GO:2000810 IEA
Subcellular Localization
    stereocilium membrane GO:0060171 IEA
    cytoplasmic membrane-bounded vesicle GO:0016023 IEA
    extracellular exosome GO:0070062 IEA
    membrane raft GO:0045121 IEA
    nucleolus GO:0005730 IEA
    basal plasma membrane GO:0009925 IEA
    lateral plasma membrane GO:0016328 IEA
    myosin I complex GO:0045160 IEA
    ruffle GO:0001726 IEA
    nuclear pore GO:0005643 IEA
    nucleoplasm GO:0005654 IEA
    mitochondrion GO:0005739 IEA
    brush border GO:0005903 IEA
    filamentous actin GO:0031941 IEA
 Experiment description of studies that identified MYO1C in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MYO1C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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