Gene description for Aldh7a1
Gene name aldehyde dehydrogenase 7 family, member A1
Gene symbol Aldh7a1
Other names/aliases antiquitin
Species Rattus norvegicus
 Database cross references - Aldh7a1
ExoCarta ExoCarta_291450
Entrez Gene 291450
UniProt Q64057  
 Aldh7a1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Aldh7a1
Molecular Function
    aldehyde dehydrogenase (NAD) activity GO:0004029 IBA
    L-aminoadipate-semialdehyde dehydrogenase activity GO:0004043 ISO
    betaine-aldehyde dehydrogenase activity GO:0008802 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    glycine betaine biosynthetic process from choline GO:0019285 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 ISO
    cytosol GO:0005829 IEA
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Aldh7a1 in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Aldh7a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aldh7a1 is involved
PathwayEvidenceSource
Lysine catabolism IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here