Gene description for Cfb
Gene name complement factor B
Gene symbol Cfb
Other names/aliases Bf
Da1-24
Species Rattus norvegicus
 Database cross references - Cfb
ExoCarta ExoCarta_294257
Entrez Gene 294257
 Cfb identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Cfb
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
Biological Process
    complement activation, alternative pathway GO:0006957 ISO
    complement activation GO:0006956 IDA
    response to lipopolysaccharide GO:0032496 IEP
    proteolysis GO:0006508 IEA
    response to thyroid hormone GO:0097066 IMP
Subcellular Localization
    extracellular space GO:0005615 ISO
    extracellular exosome GO:0070062 ISO
    blood microparticle GO:0072562 ISO
 Experiment description of studies that identified Cfb in exosomes
1
Experiment ID 95
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Cfb
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cfb is involved
No pathways found





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