Gene description for Coro1b
Gene name coronin, actin-binding protein, 1B
Gene symbol Coro1b
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Coro1b
ExoCarta ExoCarta_29474
Entrez Gene 29474
UniProt O89046  
 Coro1b identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Coro1b
Molecular Function
    Arp2/3 complex binding GO:0071933 ISO
    identical protein binding GO:0042802 ISO
    actin filament binding GO:0051015 ISO
Biological Process
    actin filament bundle assembly GO:0051017 ISO
    negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316 ISO
    cell migration GO:0016477 ISO
    cellular response to platelet-derived growth factor stimulus GO:0036120 ISO
    wound healing GO:0042060 ISO
    protein localization to cell leading edge GO:1902463 ISO
    ruffle organization GO:0031529 ISO
    negative regulation of smooth muscle cell chemotaxis GO:0071672 ISO
    positive regulation of lamellipodium morphogenesis GO:2000394 ISO
    negative regulation of lamellipodium morphogenesis GO:2000393 IMP
    actin filament branching GO:0090135 ISO
    actin cytoskeleton organization GO:0030036 ISO
    regulation of Arp2/3 complex-mediated actin nucleation GO:0034315 IC
    endothelial cell chemotaxis GO:0035767 ISO
Subcellular Localization
    cell leading edge GO:0031252 ISO
    perinuclear region of cytoplasm GO:0048471 ISO
    stress fiber GO:0001725 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
    cell periphery GO:0071944 ISO
    actin filament GO:0005884 ISO
    focal adhesion GO:0005925 ISO
    lamellipodium GO:0030027 ISO
    actin cytoskeleton GO:0015629 IBA
    plasma membrane GO:0005886 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Coro1b in exosomes
1
Experiment ID 95
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
3
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Coro1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Coro1b is involved
No pathways found





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