Gene description for Copa
Gene name coatomer protein complex subunit alpha
Gene symbol Copa
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Copa
ExoCarta ExoCarta_304978
Entrez Gene 304978
 Copa identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Copa
Molecular Function
    structural molecule activity GO:0005198 IEA
Biological Process
    vesicle-mediated transport GO:0016192 IEA
    pancreatic juice secretion GO:0030157 ISO
    intracellular protein transport GO:0006886 IEA
Subcellular Localization
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 ISO
    COPI vesicle coat GO:0030126 ISO
    extracellular exosome GO:0070062 ISO
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Copa in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Copa
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Copa is involved
No pathways found





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