Gene description for Pisd
Gene name phosphatidylserine decarboxylase
Gene symbol Pisd
Other names/aliases 9030221M09Rik
Species Mus musculus
 Database cross references - Pisd
ExoCarta ExoCarta_320951
Entrez Gene 320951
UniProt Q8BSF4  
 Pisd identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pisd
Molecular Function
    lyase activity GO:0016829 IEA
    phosphatidylserine decarboxylase activity GO:0004609 IEA
    carboxy-lyase activity GO:0016831 IEA
Biological Process
    lipid metabolic process GO:0006629 IEA
    phospholipid biosynthetic process GO:0008654 IEA
Subcellular Localization
    mitochondrion GO:0005739 IDA
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Pisd in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pisd
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pisd is involved
PathwayEvidenceSource
Synthesis of PE IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here