Gene description for Ptprk
Gene name protein tyrosine phosphatase, receptor type, K
Gene symbol Ptprk
Other names/aliases Rptpk
Species Rattus norvegicus
 Database cross references - Ptprk
ExoCarta ExoCarta_360302
Entrez Gene 360302
 Ptprk identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ptprk
Molecular Function
    protein kinase binding GO:0019901 ISO
    protein tyrosine phosphatase activity GO:0004725 TAS
    gamma-catenin binding GO:0045295 ISO
    beta-catenin binding GO:0008013 ISO
Biological Process
    cell adhesion GO:0007155 ISO
    negative regulation of transcription, DNA-templated GO:0045892 ISO
    neuron projection development GO:0031175 IMP
    focal adhesion assembly GO:0048041 ISO
    peptidyl-tyrosine dephosphorylation GO:0035335 ISO
    protein localization to cell surface GO:0034394 ISO
    signal transduction GO:0007165 ISO
    cell migration GO:0016477 ISO
    negative regulation of cell cycle GO:0045786 ISO
    negative regulation of keratinocyte proliferation GO:0010839 ISO
    protein dephosphorylation GO:0006470 ISO
    negative regulation of cell proliferation GO:0008285 ISO
    transforming growth factor beta receptor signaling pathway GO:0007179 ISO
    cellular response to UV GO:0034644 ISO
    cellular response to reactive oxygen species GO:0034614 ISO
    negative regulation of cell migration GO:0030336 ISO
Subcellular Localization
    leading edge membrane GO:0031256 ISO
    dendrite GO:0030425 ISO
    cell surface GO:0009986 ISO
    neuronal cell body GO:0043025 ISO
    axon GO:0030424 ISO
    photoreceptor outer segment GO:0001750 ISO
    cell-cell junction GO:0005911 ISO
 Experiment description of studies that identified Ptprk in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ptprk
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ptprk is involved
No pathways found





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