Gene description for C2cd5
Gene name C2 calcium-dependent domain containing 5
Gene symbol C2cd5
Other names/aliases RGD1304592
Species Rattus norvegicus
 Database cross references - C2cd5
ExoCarta ExoCarta_362461
Entrez Gene 362461
 C2cd5 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for C2cd5
Molecular Function
    calcium ion binding GO:0005509 ISO
    calcium-dependent phospholipid binding GO:0005544 ISO
Biological Process
    vesicle fusion GO:0006906 ISO
    intracellular protein transmembrane transport GO:0065002 ISO
    positive regulation of vesicle fusion GO:0031340 ISO
    cellular response to insulin stimulus GO:0032869 ISO
    protein localization to plasma membrane GO:0072659 ISO
    positive regulation of glucose import in response to insulin stimulus GO:2001275 ISO
    positive regulation of protein targeting to membrane GO:0090314 ISO
    positive regulation of glucose transport GO:0010828 ISO
    insulin receptor signaling pathway via phosphatidylinositol 3-kinase GO:0038028 ISO
Subcellular Localization
    plasma membrane GO:0005886 ISO
    cell cortex GO:0005938 ISO
    microtubule organizing center GO:0005815 ISO
    cytoplasmic vesicle membrane GO:0030659 ISO
    ruffle membrane GO:0032587 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified C2cd5 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for C2cd5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which C2cd5 is involved
No pathways found





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