Gene description for Trappc4
Gene name trafficking protein particle complex 4
Gene symbol Trappc4
Other names/aliases Sbdn
Species Rattus norvegicus
 Database cross references - Trappc4
ExoCarta ExoCarta_367073
Entrez Gene 367073
UniProt Q69BT7  
 Trappc4 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Trappc4
Molecular Function
    Rab guanyl-nucleotide exchange factor activity GO:0017112 IBA
Biological Process
    ER to Golgi vesicle-mediated transport GO:0006888 IBA
    dendrite development GO:0016358 ISO
    positive regulation of GTPase activity GO:0043547 IBA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IEA
    synaptic vesicle GO:0008021 ISO
    cis-Golgi network GO:0005801 IEA
    TRAPP complex GO:0030008 ISO
    Golgi stack GO:0005795 ISO
    dendrite GO:0030425 ISO
    synapse GO:0045202 ISO
 Experiment description of studies that identified Trappc4 in exosomes
1
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Trappc4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Trappc4 is involved
PathwayEvidenceSource
Syndecan interactions IEA Reactome





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