Gene description for cindr
Gene name CIN85 and CD2AP orthologue
Gene symbol cindr
Other names/aliases BcDNA:GH03163
CD2AP
CG11316
CG1408
CG31012
Cindr
DmelCG31012
Species Drosophila melanogaster
 Database cross references - cindr
ExoCarta ExoCarta_43654
Entrez Gene 43654
 cindr identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for cindr
Molecular Function
    SH3 domain binding GO:0017124 IDA
    cell adhesion molecule binding GO:0050839 IPI
    SH3/SH2 adaptor activity GO:0005070 ISS
Biological Process
    intercellular bridge organization GO:0043063 IMP
    compound eye morphogenesis GO:0001745 IMP
    positive regulation of receptor-mediated endocytosis GO:0048260 IGI
    border follicle cell migration GO:0007298 IMP
    compound eye development GO:0048749 IMP
    actin filament organization GO:0007015 IMP
    regulation of cytokinesis GO:0032465 IMP
    lateral inhibition GO:0046331 IMP
Subcellular Localization
    midbody GO:0030496 IDA
    cleavage furrow GO:0032154 IDA
    intercellular bridge GO:0045171 IDA
 Experiment description of studies that identified cindr in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for cindr
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which cindr is involved
No pathways found





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