Gene description for HOMER1
Gene name homer homolog 1 (Drosophila)
Gene symbol HOMER1
Other names/aliases -
Species Bos taurus
 Database cross references - HOMER1
ExoCarta ExoCarta_535311
Entrez Gene 535311
UniProt Q2KJ56  
 HOMER1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HOMER1
Molecular Function
    G-protein coupled glutamate receptor binding GO:0035256 IBA
    ion channel binding GO:0044325 IEA
Biological Process
    regulation of calcium ion import GO:0090279 IEA
    response to calcium ion GO:0051592 IEA
    chemical homeostasis within a tissue GO:0048875 IEA
    regulation of store-operated calcium entry GO:2001256 IBA
    positive regulation of calcium ion transport GO:0051928 IEA
    regulation of cation channel activity GO:2001257 IEA
    skeletal muscle contraction GO:0003009 IEA
    skeletal muscle fiber development GO:0048741 IEA
    G-protein coupled glutamate receptor signaling pathway GO:0007216 IBA
    behavioral response to cocaine GO:0048148 IEA
Subcellular Localization
    postsynaptic membrane GO:0045211 IEA
    neuronal postsynaptic density GO:0097481 IBA
    Z disc GO:0030018 IEA
    apical part of cell GO:0045177 IEA
    plasma membrane GO:0005886 IBA
    axon GO:0030424 IEA
    cell junction GO:0030054 IEA
    costamere GO:0043034 IEA
 Experiment description of studies that identified HOMER1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HOMER1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HOMER1 is involved
No pathways found





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