Gene description for Cpa3
Gene name carboxypeptidase A3, mast cell
Gene symbol Cpa3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Cpa3
ExoCarta ExoCarta_54242
Entrez Gene 54242
UniProt P21961  
 Cpa3 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Cpa3
Molecular Function
    zinc ion binding GO:0008270 IEA
    peptidase activity GO:0008233 ISO
    metallocarboxypeptidase activity GO:0004181 IEA
Biological Process
    proteolysis GO:0006508 ISO
    positive regulation of defense response to virus by host GO:0002230 ISO
    regulation of angiotensin levels in blood GO:0002002 ISO
Subcellular Localization
    transport vesicle GO:0030133 IEA
 Experiment description of studies that identified Cpa3 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Cpa3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cpa3 is involved
PathwayEvidenceSource
Metabolism of Angiotensinogen to Angiotensins IEA Reactome





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