Gene description for Rhog
Gene name ras homolog gene family, member G
Gene symbol Rhog
Other names/aliases 2810426G09Rik
Arhg
Sid10750
Species Mus musculus
 Database cross references - Rhog
ExoCarta ExoCarta_56212
Entrez Gene 56212
UniProt P84096  
 Rhog identified in exosomes derived from the following tissue/cell type
Microglia 16081791    
 Gene ontology annotations for Rhog
Molecular Function
    nucleotide binding GO:0000166 IEA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
    GTPase activity GO:0003924 ISO
Biological Process
    metabolic process GO:0008152 ISO
    positive regulation of transcription, DNA-templated GO:0045893 ISO
    regulation of ruffle assembly GO:1900027 IDA
    Rac protein signal transduction GO:0016601 ISO
    cell chemotaxis GO:0060326 ISO
    small GTPase mediated signal transduction GO:0007264 IEA
    actin cytoskeleton organization GO:0030036 ISO
    activation of GTPase activity GO:0090630 ISO
    positive regulation of establishment of protein localization to plasma membrane GO:0090004 ISO
    Rho protein signal transduction GO:0007266 ISO
Subcellular Localization
    focal adhesion GO:0005925 ISO
    intracellular GO:0005622 ISO
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Rhog in exosomes
1
Experiment ID 14
ISEV standards
EM
EV Biophysical techniques
RAB7|RAB11
EV Cytosolic markers
CD9|CD63|LAMP1|LAMP2
EV Membrane markers
DNM
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 16081791    
Organism Mus musculus
Experiment description Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism.
Authors Potolicchio I, Carven GJ, Xu X, Stipp C, Riese RJ, Stern LJ, Santambrogio L
Journal name JIMMU
Publication year 2005
Sample Microglia
Sample name N9
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
 Protein-protein interactions for Rhog
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SMAD4  
Affinity Capture-Luminescence Homo sapiens
View the network image/svg+xml



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