Gene description for SKP1
Gene name S-phase kinase-associated protein 1
Gene symbol SKP1
Other names/aliases SKP1A
Species Bos taurus
 Database cross references - SKP1
ExoCarta ExoCarta_615427
Entrez Gene 615427
UniProt Q3ZCF3  
 SKP1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SKP1
Molecular Function
    ubiquitin-protein transferase activity GO:0004842 IEA
Biological Process
    histone H2A monoubiquitination GO:0035518 IEA
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146 ISS
Subcellular Localization
    SCF ubiquitin ligase complex GO:0019005 ISS
    extracellular exosome GO:0070062 IEA
    Cul7-RING ubiquitin ligase complex GO:0031467 ISS
    PcG protein complex GO:0031519 IEA
    cytosol GO:0005829 ISS
 Experiment description of studies that identified SKP1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SKP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SKP1 is involved
No pathways found

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