Gene description for Rpf2
Gene name ribosome production factor 2 homolog (S. cerevisiae)
Gene symbol Rpf2
Other names/aliases 2810470K21Rik
AU040229
AU043242
Bxdc1
Species Mus musculus
 Database cross references - Rpf2
ExoCarta ExoCarta_67239
Entrez Gene 67239
UniProt Q9JJ80  
 Rpf2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rpf2
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    rRNA binding GO:0019843 IBA
Biological Process
    maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000463 IBA
    ribosomal large subunit assembly GO:0000027 IBA
    biological_process GO:0008150 ND
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleolus GO:0005730 ISO
 Experiment description of studies that identified Rpf2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rpf2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rpf2 is involved
No pathways found





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