Gene description for Fbn2
Gene name fibrillin 2
Gene symbol Fbn2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fbn2
ExoCarta ExoCarta_689008
Entrez Gene 689008
 Fbn2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Fbn2
Molecular Function
    calcium ion binding GO:0005509 IEA
    extracellular matrix structural constituent GO:0005201 IEA
Biological Process
    sequestering of TGFbeta in extracellular matrix GO:0035583 ISO
    positive regulation of osteoblast differentiation GO:0045669 ISO
    bone trabecula formation GO:0060346 ISO
    positive regulation of bone mineralization GO:0030501 ISO
    limb morphogenesis GO:0035108 ISO
    embryonic limb morphogenesis GO:0030326 ISO
Subcellular Localization
    proteinaceous extracellular matrix GO:0005578 IEA
    extracellular matrix GO:0031012 ISO
    extracellular region GO:0005576 ISO
    microfibril GO:0001527 ISO
 Experiment description of studies that identified Fbn2 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Fbn2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fbn2 is involved
No pathways found





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