Gene description for Lrrc15
Gene name leucine rich repeat containing 15
Gene symbol Lrrc15
Other names/aliases 5430427N11Rik
LIB
Species Mus musculus
 Database cross references - Lrrc15
ExoCarta ExoCarta_74488
Entrez Gene 74488
UniProt Q80X72  
 Lrrc15 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Lrrc15
Molecular Function
    laminin binding GO:0043236 ISO
    collagen binding GO:0005518 ISO
    fibronectin binding GO:0001968 ISO
Biological Process
    negative regulation of establishment of protein localization to plasma membrane GO:0090005 ISO
    positive regulation of cell migration GO:0030335 ISO
    receptor-mediated virion attachment to host cell GO:0046813 ISO
Subcellular Localization
    intracellular GO:0005622 ISO
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Lrrc15 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Lrrc15
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lrrc15 is involved
No pathways found





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