Gene description for Cyba
Gene name	cytochrome b-245, alpha polypeptide
Gene symbol	Cyba
Other names/aliases	p22-phox
Species	Rattus norvegicus
Database cross references - Cyba
ExoCarta	ExoCarta_79129
Entrez Gene	79129
UniProt	Q62737
Cyba identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells	20124479
Pancreatic cancer cells	20124479
Reticulocytes	21828046

Gene ontology annotations for Cyba

Molecular Function     protein heterodimerization activity GO:0046982 ISO     electron carrier activity GO:0009055 ISO     heme binding GO:0020037 IEA     SH3 domain binding GO:0017124 ISO     superoxide-generating NADPH oxidase activity GO:0016175 ISO     metal ion binding GO:0046872 IEA     protein binding GO:0005515 IPI Biological Process     positive regulation of interleukin-6 production GO:0032755 ISO     cellular response to gamma radiation GO:0071480 IEP     response to interleukin-1 GO:0070555 IEP     hydrogen peroxide biosynthetic process GO:0050665 IMP     positive regulation of defense response to bacterium GO:1900426 ISO     positive regulation of reactive oxygen species biosynthetic process GO:1903428 ISO     positive regulation of mucus secretion GO:0070257 ISO     smooth muscle hypertrophy GO:0014895 IMP     cellular response to mechanical stimulus GO:0071260 IEP     superoxide anion generation GO:0042554 ISO     regulation of blood pressure GO:0008217 IMP     positive regulation of tumor necrosis factor production GO:0032760 ISO     response to drug GO:0042493 IEP     regulation of release of sequestered calcium ion into cytosol GO:0051279 ISO     positive regulation of toll-like receptor 2 signaling pathway GO:0034137 ISO     cellular response to organic cyclic compound GO:0071407 IEP     superoxide metabolic process GO:0006801 ISO     reactive oxygen species metabolic process GO:0072593 ISO     oxidation-reduction process GO:0055114 ISO     cellular response to amino acid stimulus GO:0071230 IEP     positive regulation of phagocytosis GO:0050766 ISO     response to nutrient levels GO:0031667 IEP     cellular response to tumor necrosis factor GO:0071356 IEP     inflammatory response GO:0006954 ISO     positive regulation of smooth muscle cell proliferation GO:0048661 IMP     cytochrome complex assembly GO:0017004 ISO     innate immune response GO:0045087 ISO     positive regulation of endothelial cell proliferation GO:0001938 IMP     negative regulation of glomerular filtration by angiotensin GO:0003106 IMP     respiratory burst GO:0045730 ISO     cellular response to glucose stimulus GO:0071333 IEP     positive regulation of superoxide anion generation GO:0032930 IMP     cellular response to organic substance GO:0071310 IDA     positive regulation of cell growth GO:0030307 IMP Subcellular Localization     perinuclear endoplasmic reticulum GO:0097038 IDA     dendrite GO:0030425 IDA     membrane GO:0016020 ISO     NADPH oxidase complex GO:0043020 ISO     endosome GO:0005768 ISO     neuronal cell body GO:0043025 IDA     apical plasma membrane GO:0016324 IDA     cytoplasm GO:0005737 ISO     Golgi apparatus GO:0005794 IDA     mitochondrion GO:0005739 ISO