Gene description for Nucks1
Gene name nuclear casein kinase and cyclin-dependent kinase substrate 1
Gene symbol Nucks1
Other names/aliases 2700010L10Rik
8430423A01Rik
AI647518
C78391
Nucks
Species Mus musculus
 Database cross references - Nucks1
ExoCarta ExoCarta_98415
Entrez Gene 98415
UniProt Q80XU3  
 Nucks1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nucks1
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Nucks1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nucks1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nucks1 is involved
No pathways found





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