| EXO-Quant : |
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ExoCarta, a freely accessible web-based compendium of sEV studies that encompasses DNA, RNA, proteins, and lipids that are detected in sEVs.
QUANT, a new plugin that enables the relative quantification of sEV cargo between different samples within a single study or experiment. For studies where quantification data is available, it has been carefully annotated in accordance with the original authors' specified formats, such as normalized spectral count (NSPC), label-free quantification (LFQ) intensity, log2 fold change, or other relevant metrics. We have ensured that studies originating from the same experiment and deemed suitable for comparison are annotated using consistent metrics, facilitating comparisons exclusively within the appropriate datasets. QUANT provides a searchable, interactive data table listing all the contents identified in an experiment between conditions. Users can search for biomolecule of interest and compare between conditions in real time. The top 100 differentially abundant cargos between the selected experiments will be automatically visualized using a heatmap |
Want to contribute to ExoCarta?
We will keep ExoCarta updated with new sEV studies. We would love to have scientific community participation in any of the following ways.
Send unpublished sEV proteome/RNA/lipid datasets (it can be made private until published)
Point out an sEV publication that we missed
Contact us either to upload your sEV data or point to us if we have not added any published sEV study.
ExoCarta citation:
Keerthikumar, S., Chisanga, D., Ariyaratne, D., Al Saffar, H., Anand, S., Zhao, K., Samuel, M., Pathan, M., Jois, M., Chilamkurti, N., Gangoda, L. and Mathivanan, S. ExoCarta: A web-based compendium of exosomal cargo.
Journal of Molecular Biology. 2015.
PubMed
Simpson, R.J., Kalra, H. and Mathivanan, S. ExoCarta as a resource for exosomal research Journal of Extracellular Vesicles. 2012.
PubMed
Mathivanan, S. Fahner, C.J., Reid, G.E., and Simpson, R.J. ExoCarta 2012: database of exosomal proteins, RNA and lipids. Nucleic Acids Research. 2012.
PubMed
Mathivanan, S. and Simpson, R.J. ExoCarta: A compendium of exosomal proteins and RNA. Proteomics. 2009. 21, 4997-5000.
PubMed
sEV reviews:
1. Simpson RJ and Mathivanan S. Extracellular Microvesicles: The Need for Internationally Recognised Nomenclature and Stringent Purification Criteria J Proteomics Bioinform. 2012. PubMed
2. Thery C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol. 2009. 8, 581-93. PubMed
3. Keller S, Sanderson MP, Stoeck A, Altevogt P. Exosomes: from biogenesis and secretion to biological function. Immunol Lett. 2006. 2, 102-8. PubMed
4. Simpson RJ, Lim JW, Moritz RL, Mathivanan S. Exosomes: proteomic insights and diagnostic potential. Expert Rev Proteomics. 2009. 3, 267-83. PubMed
5. Record M, Subra C, Silvente-Poirot S, Poirot M. Exosomes as intercellular signalosomes and pharmacological effectors. Biochem Pharmacol. 2011.10, 1171-82. PubMed
6. Cocucci E, Racchetti G, Meldolesi J. Shedding microvesicles: artefacts no more. Trends Cell Biol. 2009. 2, 43-51. PubMed
7. Schorey JS, Bhatnagar S. Exosome function: from tumor immunology to pathogen biology. Traffic. 2008. 6, 871-81. PubMed
8. Mathivanan S, Ji H, Simpson RJ. Exosomes: Extracellular organelles important in intercellular communication. Journal of Proteomics. 2010. PubMed
9. van Niel G, Porto-Carreiro I, Simoes S, Raposo G. Exosomes: a common pathway for a specialized function. J Biochem. 2006. 1, 13-21. PubMed
10. Johnstone RM. Exosomes biological significance: A concise review. Blood Cells Mol Dis. 2006. 2, 315-21. PubMed
More exosome articles .....
| For more options to search data by tissue/cell-type or organism please refer to | Browse | page. |