Gene description for Unc5b
Gene name
unc-5 homolog B (C. elegans)
Gene symbol
Unc5b
Other names/aliases
6330415E02Rik A630020F16 D10Bwg0792e Unc5h2
Species
Mus musculus
Database cross references - Unc5b
ExoCarta
ExoCarta_107449
Vesiclepedia
VP_107449
Entrez Gene
107449
UniProt
Q8K1S3
Unc5b identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Unc5b
Experiment description of studies that identified Unc5b in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Unc5b
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Nphs2
Affinity Capture-MS
Mus musculus
2
Ppp2r1a
51792
Affinity Capture-Western
Mus musculus
Affinity Capture-Western
Mus musculus
3
Ppp2r1b
73699
Affinity Capture-Western
Mus musculus
Affinity Capture-Western
Mus musculus
4
Ppp2ca
19052
Affinity Capture-Western
Mus musculus
View the network
image/svg+xml
Pathways in which Unc5b is involved
No pathways found